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Showing 1 to 12 of 12 for “"Glomerular basement membrane"”.

  1. Quantitative Studies Of The Interaction Of Immunoglobulin-G With Glomerular Basement Membrane.

    Hillock, Ronald Henry

    uab Repository record

  2. Nephrotic Syndrome and Glomerular Basement Membrane: Genetic Defect of the Laminin α5 Chain

    Falcone, SaraThe Open University2018

    … and laminin γ1, it is a major component of the glomerular basement membrane. Mutations in <i>LAMB2</i> are associated with Pierson’s syndrome and mutations in <i>LAMA5</i> have recently been identified in paediatric patients affected by nephrotic syndrome. <br></br><br></br> As part of the MRC …

    the-open-u Repository record

  3. A Glomerular Basement Membrane-on-a-Chip Model for Investigating Charge-Selective Transport Across the Human Filtration Barrier

    Pardawala, NakiyaUniversity of Saskatchewan2026

    … the body. However, during dialysis, blood–membrane interactions activate the coagulation cascade and complement system, leading to protein adsorption on the membrane surface, impaired filtration, and adverse patient outcomes. This underscores the need for biocompatible membranes that better …

    sask Repository record

  4. Factors affecting severity of injury in allergic renal disease

    Van Zyl-Smit, RoalDepartment of Medicine1983

    … raised in sheep, containing antibodies to rabbit glomerular basement membrane. In a second group of experiments, the induction of an acute phase response in rabbits by the subcutaneous injection of a local irritant was studied. It was characterised by changes in C-reactive protein (CRP), the third …

    cape-town Repository record

  5. Hindered transport in composite hydrogels

    Kosto, Kimberly Bryan, 1977-Massachusetts Institute of Technology2004

    … needed to describe transport within the glomerular basement membrane (GBM). Specifically, dimensionless diffusive and convective hindrance factors were investigated by measuring macromolecular permeability through synthetic, two-fiber, agarose-dextran hydrogels at very small or very high …

    mit Repository record

  6. Studies of ADAMTS13 expression and activity in the kidney

    Tati, RameshPaediatrics, Faculty of Medicine, Lund University2013

    … tubulopathy suggesting local synthesis. Cultured glomerular endothelial cells were also shown to express biologically active ADAMTS13. ADAMTS13-deficiency in mice led to glomerular capillary vessel wall thickening and platelet deposition as demonstrated by electron microscopy. ADAMTS13 was also …

    lund Repository record

  7. Conjugated Linoleic Acid in the treatment of murine autoimmune glomerulonephritis

    Hammond, Sarah ElizabethVirginia Tech2015

    … mesangial cells, and in murine models of anti-glomerular basement membrane (anti-GBM) glomerulonephritis and Systemic Lupus Erythematosus (SLE). SV40-transformed mouse mesangial cells (MES13) were cultured with pure CLA isomers (c9,t11 or t10,c12-CLA or a 50:50 mixture prior to immune …

    vt Repository record

  8. FUZZY METHODS FOR OBJECT RECOGNITION

    XIAOFAN LIU1996

    … is tested by applying it to the detection of the glomerular basement membrane in kidney electron micrographs.

    nus Repository record

  9. A ten year retrospective study of the aetiology and outcome of crescentic glomerulonephritis in children presenting to the Red Cross Children's Hospital, Cape Town, South Africa

    Mwaba, ChisamboDepartment of Paediatrics and Child Health2017

    … represents the extreme end on the spectrum of glomerular injury. It can result from a wide range of disease conditions and clinically is marked by a rapid deterioration in renal function over days, weeks or months. Although rare, crescentic glomerulonephritis is an important entity to recognize …

    cape-town Repository record

  10. Functional, Structural and Molecular Alterations in the Heart and Kidney During Diabetes Mellitus

    Waqar, TehreemUniversity of Central Lancashire2016

    … whereas the kidney presented with increase glomerular basement membrane thickness in T1DM compared to controls. These data clearly show that adult vs young adult, in combination with STZ-induced T1DM, can elicit severe changes to both the heart and the kidney, respectively in structural, …

    cent-lancashire Repository record

  11. Effects of plasma proteins on the sieving of macromolecular tracers in the kidney

    Lazzara, Matthew JMassachusetts Institute of Technology2003

    … waste and retain desirable substances. The glomerular barrier has long been regarded as both a size and charge selective screen for plasma solutes. The origin of this selectivity is found in the unique three-layered structure of the glomerular capillary wall (GCW), consisting of a …

    mit Repository record

  12. Die Bedeutung des Kollagenrezeptors α2β1- Integrin bei der Pathogenese und Prävention der Nierenfibrose in hereditären Typ IV- Kollagen- Erkrankungen

    Martin, Maria2012

    … IV hat als einer der Hauptbestandteile von Basalmembranen eine Struktur gebende Funktion und ist als Ligand an Rezeptoren der Zelle bei der Vermittlung von Signalkaskaden, die Zellfunktionen, Wachstums- und Differenzierungsprozesse beeinflussen maßgeblich beteiligt. Aufgrund seiner weit …

    goettingen Repository record