Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Globoid-cell Leukodystrophy"”.
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The Role Of Inflammation In Pathogenesis And Treatment Of Globoid-Cell Leukodystrophy
Globoid-cell leukodystrophy: GLD, Krabbe's disease) is an autosomal recessive disease caused by a deficiency of the lysosomal enzyme galactosylceramidase: GALC). It results in altered catabolism of the myelin lipid Galactosylceramide. The disease predominantly affects the white matter of the CNS …
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MENINGES AS AN OVERLOOKED TARGET FOR GLOBOID CELL LEUKODISTROPHY
Globoid cell leukodystrophy (GLD), also known as Krabbe disease, is a severe neurological disorder caused by the deficiency of galactocerebrosidase (GALC) enzyme, leading to the accumulation of toxic metabolites and ultimately resulting in progressive demyelination and neurodegeneration. The only …
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Expansion of the New York State Newborn Screening Panel and Krabbe Disease: A Systematic Program Evaluation
The purpose of this study was to conduct a formal program evaluation of the New York State newborn screening for Krabbe disease (KD), a rare neurological disease with variable onset of symptoms to assess 1) the perceptions of stakeholders 2) KD test characteristics, and 3) actual program costs. …