Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Global regulators"”.
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Investigation of global regulators influencing styrene metabolism and bioplastic synthesis in Pseudomonas putida CA-3
… to date. Knowledge of the role played by global regulators in controlling these pathways currently represents a critical knowledge gap in this area. Here we report on our efforts to identify such regulators using mini-Tn5 transposon mutagenesis of the P. putida CA-3 genome. The library …
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Integration and Excision Mechanism of Bacteroides Conjugative Transposons
… of RteB on CTnDOT. RteA and RteB are shown to be global regulators that regulate many genes on Bacteroides host. Whether RteB regulates CTnDOT and NBU1 excision directly or not is investigated in this study. Both RteB and the mutant are over-expressed in E. coli and partially purified. RteB is a …
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Regulatory Genes of the Bacteroides Conjugative Transposon, CTnDOT
… RT-PCR analyses. I showed that RteA and RteB are global regulators that induce the expression of various genes, in particular, tra genes in CTn, a cryptic CTn found in the chromosome. In addition, I characterized the repressor region, rteR, which regulates the expression of tra genes, using …
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Nucleoid-Associated Proteins of Streptomyces coelicolor: Discovery and Functions
… such as HupA, HupS, Lsr2 and sIHF and the known global regulators CRP and BldD, as well as a number of interesting novel NAP candidates from a variety of protein classes suitable for further investigation. One of these proteins, SCO5592, was investigated as a candidate global RNA-binding …
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Ehrlichia chaffeensis TRP32 is a Nucleomodulin that Regulates Host Gene Expression and Post-Translational Modifications Determine its Localization and Function
… on all chromosomes and included several global regulators of proliferation and inflammation such as FOS and JUN, AKT3 and NRAS, and non-coding RNA genes, miRNA 21 and miRNA 142. TRP32 target genes were differentially regulated during infection, and direct repression/activation of these …
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Role of msaA Gene in Regulation of the msaABCR Operon and Biofilm Development in <i>Staphylococcus aureus</i>
… that are controlled by a complex network of global virulence regulators, and they make this pathogen more successful compared to other MRSA strains. In previous study, we have shown that the <em>msaABCR</em> is a new four gene operon that globally regulates virulence and biofilm development …
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Regulation of the Mannose PTS Operon by the small RNA SgrS
A number of bacterial small RNAs (sRNAs) act as global regulators of stress responses by controlling expression of multiple genes. The sRNA SgrS is expressed in response to glucose-phosphate stress, a condition associated with disruption of glycolytic flux and accumulation of sugar-phosphates. SgrS …
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Functional analysis of selected DOF transcription factors in the model plant Arabidopsis thaliana
Transcription factors (TFs) are global regulators of gene expression playing essential roles in almost all biological processes, and are therefore of great scientific and biotechnological interest. This project focused on functional characterisation of three DNA-binding-with-one-zinc-finger (DOF) …
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Essays on ESG Disclosure Policies
… in emerging markets.</p> <p>Chapter 1: As global regulators increasingly adopt non-financial disclosure mandates, understanding the design and effectiveness of such policies has become critical. This paper evaluates the impact of Hong Kong’s staggered ESG (Environmental, Social, and …
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Genomic investigation into the evolution of <i>Staphylococcus aureus</i> and the micro-epidemiology of <i>Staphylococcus aureus </i>in atopic eczema
… of carriage, and included examples affecting global regulators of virulence and antimicrobial resistance. This analysis also revealed segregation in the genetic backgrounds of strains preferentially colonising AE skin in comparison to nasal epithelium, and evidence of the impact of prescribing …
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Mechanisms of Regulation and Resistance for Plasmid-Encoded ampC Beta-Lactamase Genes
… promoter hypothesized to be under the control of global regulators involved in cell metabolism. RNA expression levels were correlated with gene copy number and BETA-lactam MICs for the organisms from which the plasmid-encoded ampC genes were expressed. It was determined from these studies that the …
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Evolutionary and functional analysis of transcription factors controlling leaf development
… gene expression. Transcription factors (TFs) are global regulators of gene expression that play essential roles in almost all biological processes among eukaryotes. This PhD project focused on the characterization of the sink-to-source transition of Arabidopsis leaves and on the analysis of TFs …