Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 130 for “"Global public health"”.
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Novel Applications of Syndemic Theory for Global Public Health: Considerations for Gender Based Violence and Mixed Methods Research
… and analytical approaches as well as global health applications. Three research aims scaffold this overall goal. In Aim 1, I conducted a systematic review of quantitative research that tested syndemic theories involving GBV the context of LMICs. The following research questions guided …
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In silico vaccine design for hepatitis C: A computational platform for fighting disease
… liver morbidity and mortality and a scourge to global public health. Despite more than 20 years of research, only recently have effective treatments been developed and a vaccine remains elusive. The high cost of efficacious drug treatments severely limits their impact in the developing world, …
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The assessment of the contamination of soil-transmitted helminth life stages in the environment and under fingernails
… duodenale). STHs pose an important threat to global public health, affecting the poorest and most deprived communities where sanitation is inadequate, and water supplies are unsafe. Large-scale deworming programs have been successful in reducing the burden of disease due to STH infections, but …
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Modeling Emerging Infectious Diseases for Public Health Decision Support
… diseases (EID) pose a serious threat to global public health. Computational epidemiology is a nascent subfield of public health that can provide insight into an outbreak in advance of traditional methodologies. Research in this dissertation will use fuse nontraditional, publicly available …
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The prevalence and risk factors associated with pulmonary arterial hypertension among HIV-infected individuals in a tertiary hospital in Durban
… Virus (HIV) infection continues to be a major global public health burden and a risk factor for developing pulmonary arterial hypertension (PAH). Africa carries the largest burden of HIV globally. However, data summarizing the epidemiology of PAH remains unclear. The lungs are often affected by …
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Exploring parents’ experiences of living with a young person between the ages of 18–35 who is a substance abuser
… abuse is increasingly recognised as a serious global public health concern, affecting societies and families in South Africa and around the world. This study delves into the experiences of parents living with a young person, aged 18-35, who is a substance abuser in the rural Kannaland region of …
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Universal room-temperature stable influenza A nanovaccine
… of a universal IAV vaccine is paramount to global public health. The work described herein forms the basis of a universal IAV subunit nanovaccine formulation composed of a novel equine IAV antigen and IAV nucleoprotein delivered via polyanhydride nanoparticles and pentablock copolymer …
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Aggregatibacter actinomycetemcomitans serotypes in gingival crevicular fluid of mothers delivering preterm.
… before 37 weeks of gestation, is a significant global public health concern. It has a tremendous impact on both the healthcare system and the individual families affected. Low birth weight (LBW), is a direct consequence of PTB or intrauterine growth restriction, and is a major determinant of …
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Multi-site sampling and risk prioritization of antibiotic resistance genes in sewage environments
… across human and environmental habitats is a global public health challenge. In this study, we investigate the public health relevance of antibiotic resistance found in wastewater by combining metagenomic sequencing of wastewater environments with risk prioritization of resistance genes. We …
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Exploring the experiences and perceptions of adolescents and young adults of adherence to antiretroviral therapy treatment at a referral opportunistic infection clinic in Harare, Zimbabwe
… continues to have a significant impact on global public health with approximately 39 million people infected with HIV. According to estimates, there are 1.65 million adolescents living with HIV worldwide, of which 85% live in sub-Saharan Africa. While HIV/AIDS-related mortality is …
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An Application of Differential Mathematical Modeling Techniques to Study the Ongoing Rabies Epizootic in China
<p>Rabies remains a global public health issue with a wide variety of neurological symptoms such as confusion, slight paralysis, hypersalivation, and hydrophobia. Rabies is usually fatal once symptoms appear. Many species are reservoirs for rabies, such as foxes, racoons, and wild dogs, which in …
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Exploring the biofilm of Candida auris as it relates to persistence in clinical setting and susceptibility to antimicrobials
… rapid rise of drug-resistant pathogens is a global health concern. Known pathogens are acquiring resistance to many commonly used drugs, while new drug-resistant pathogens are emerging. These resistant pathogens are responsible for many healthcare-associated infections (HAI) [1, 2]. …
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Inpatient household economic burden of child malnutrition in Zimbabwe : a case study conducted at Harare Central hospital
… this illness. Although it is considered to be a global public health issue, severe acute malnutrition imposes an uneven burden on health resources across the world, with low-income countries shouldering much of this burden. Like any illness, severe acute malnutrition imposes an economic burden on …
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Beyond Virus
… pandemic, we have witnessed not only a global public health emergency but also other social crises, such as anti-Asian racism, the Black Lives Matter movement, etc. The pandemic has created an environment for potential social crises and has exacerbated existing social crises. However, …
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Gene expression profiling approach towards enhancement of malaria vaccine development
… diseases in the world, posing an enormous public health burden with significant economic consequences. The development of vaccines that provide sterile protection against pathogenic infection by the Plasmodium parasites that cause malaria is thus a major global public health priority. This …
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A meta-analysis of the prediction of violence among adults with mental disorders
… Using the state-of-the-art perspective of public health, a meta-analysis was conducted to clarify the ambiguities by synthesizing quantitative findings from 85 research reports (completed between January 1970 and May 2010) on violence risk assessment among mentally disordered adults. …
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Computational Molecular Docking Studies of Small Molecule Inhibitors With the SARS-CoV-2 Spike Protein Variants: In-Silico Drug Discovery Using Virtual Screening and Drug Repurposing Approaches
… coronavirus 2 (SARS-CoV-2) in 2019 has caused a global public health crisis of nearly unprecedented scale. In the years following the outbreak, the scientific community has mobilized to develop several vaccines and treatments. Drug repurposing as a strategy for drug development has produced many …
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Protocol and beyond: experiment and care during a TB vaccine clinical trial in South Africa
… human subjects. With a particular focus on public-sector clinical trials, a number of anthropologists have recently conducted important ethnographic research into the ground-level operations of clinical research organisations and the relationships between doctors, co-ordinators, participants …
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"But it's just paracetamol" : caregivers ability to administer over-the-counter painkillers to their children with the information provided
… (OTC) medications has become an increasing global public health concern due to the common and frequent use of painkillers among end users, to self-medicate and medicate others, without fully understanding the associated health risks. While many developed countries have started to implement …
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Exploring Mosquito Thermal Biology and Chemical Ecology in the Context of Host-Seeking and Climate Change
Mosquitoes are a significant global public health threat, claiming hundreds of thousands of lives annually due to the various pathogens they transmit, which result in diseases including dengue, malaria, and Zika. While various strategies and practices are in place to manage mosquito populations, …
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