Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Gli transcription factors"”.
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T cell receptor- and calcium-induced Gli signalling in CD8+ T cell effector function
… data from our laboratory demonstrated that Gli1, an important downstream Hh transcription factor, is important for the cytotoxic ability of murine CTLs in vitro and revealed that L-type voltage-gated Ca2+ channels (Cav1) are crucial for Gli1 induction. However, the role of Gli1 in the …
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Untersuchung des transkriptionellen Mechanismus der Igf2- Überexpression in Patched-assoziierten Tumoren
… ein Zielgen des im RMS abnormal aktivierten Shh/ Gli-Signalweges. Durch bioinformatische Recherchen wurden erstmalig fünf Gli-Konsensussequenzen im Igf2-Lokus nachgewiesen. Mittels quantitativer real-time QRT-PCR, Luziferase- und β-Galaktosidase-Assay wurde deren Funktionalität untersucht. Es …