Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Glanders"”.
-
Construction, characterization, and evaluation of CLH001 as a vaccine candidate against respiratory glanders
Burkholderia mallei is the causative agent of glanders, an incapacitating disease with high mortality rates in respiratory cases. Its endemicity and ineffectual treatment options emphasize its public health threat and highlight the need for a vaccine. In this study, we constructed and characterized …
-
Evaluation of a gold nanoparticle platform as highly immunogenic and protective therapy against Burkholderia mallei, B. pseudomallei, and Enterohemorrhagic Escherichia coli O157:H7
… pathogens and the causative agents of glanders and melioidosis. At present, effective vaccines for the prevention of glanders, or melioidosis in humans, are not available. However, renewed attention has been directed toward developing Burkholderia vaccines because of the pathogens' …
-
Characterization of the Burkholderia mallei ∆tonB Mutant and its Potential as a Backbone Attenuated Strain for Vaccine Development
… properties in acute inhalational mouse models of glanders and melioidosis infection. Compared to wild type, the B. mallei ΔtonB exhibits slower growth kinetics, siderophore hypersecretion and the inability to utilize hemin, hemoglobin and myoglobin as iron sources. A series of animal challenge …