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Showing 1 to 2 of 2 for “"Ghrelin maturation"”.

  1. Reactions for rapid access to C3a oxygenated pyrroloindolines and its application towards a novel route to pestalazine A

    … esters without electron donating groups.</p> <p> Ghrelin is a peptide hormone which plays a key role in regulating hunger and energy balance within the body. Inhibition of ghrelin O-acyltransferase (GOAT), which catalyzes an essential octanoylation step in ghrelin maturation, offers a potential …

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  2. Ghrelin Processing and Maturation: Developing a Molecular-Level Framework for Hormone Activation and Biological Function

    <p>Ghrelin is a 28 amino acid hormone involved in appetite stimulation, maintenance of energy balance, and a range of other neuroendocrine functions. Over the course of its expression and maturation, proghrelin (the prohormone of ghrelin) undergoes a unique posttranslational modification whereby a …

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