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Showing 1 to 4 of 4 for “"Germ cell biology"”.
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A Novel Transgenic Rat Model for the Study of Germ Cell Biology
… a transgenic line of rats expressing GFP in all cells of the body, a serendipitous integration of a ROSA-EGFP transgene resulted in exclusive expression of EGFP in the germ cells of both sexes. EGFP expression was uniform and robust in cleavage stage embryos beginning at the late 2-cell stage and …
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Gene expression changes during mammalian male meiotic initiation
In sexually reproducing organisms, germ cells can divide by mitosis, which generates daughter cells that are genetically identical to the mother cell, or meiosis, which divides the genome for haploid gamete generation. Germ cells undergo meiotic initiation, the transition from the mitotic cell …
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Cellular and genetic mechanisms of new tissue production in the regenerating planarian Schmidtea mediterranea
… planarian heads, require both a source for new cellular material as well as mechanisms to specify, differentiate, and pattern the regenerate. The planarian Schmidtea mediterranea is a classic system for studies of regenerative biology in which proliferating cells known as "neoblasts" provide the …
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DNA Translesion Synthesis Factors are Essential for Mammalian Embryonic Germ Cell Development
Germ cells are responsible for the transmission of genetic and epigenetic information between generations and hence alterations to the genome can have effects across generations. Faithful propagation of the genome is therefore of unique importance as mutations in the germline are the source of …