Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Genomic resource"”.
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Evaluation and annotation of Bemisia tabaci transcriptome data using paired-end RNA sequencing
… of the world’s top 100 invasive species, limited genomic resources are available in public domains. In this study, transcriptomic datasets from cassava and non-cassava colonizing B. tabaci populations were used to compare sequence divergence between populations. We sequenced transcriptomes of …
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Integrative Analysis of the Human Gut Phageome Using a Metagenomics Approach
… In this thesis, I carry out a comprehensive genomic analysis of gut phages by harnessing the biggest collection of phage genomes, gut bacteria isolates, and human gut metagenomes. I begin by introducing the Gut Phage Database (GPD) which is the largest genomic resource to date of human gut …
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Genetic variation in fast-evolving East African cichlid fishes: an evolutionary perspective
… cichlids. We generated a valuable cichlid genomic resource of five low-coverage Lake Malawi cichlid genomes, from which the general properties of the genome were characterized. Nucleotide diversity of Malawi cichlids was low at 0.26%, and a sample genotyping study found that biallelic …
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Genome-wide microscopy screening identifies links across processes including a conserved connection between DNA damage control and the microtubule cytoskeleton
… the screen, its findings and the online genomic resource SYSGRO. I then focus on a group of mutants that suggest a connection between the DNA damage response (DDR) and microtubule organisation. From here I show that the DDR induces elongation of microtubule bundles in response to the DDR …
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Improving the genome assembly and annotation of the white-tailed deer (Odocoileus virginianus borealis)
… hemorrhagic disease, and bovine tuberculosis. Genomic resources facilitate the study of pathogens, host-pathogen interactions, host genetic variation, and behavior. Repetitive elements are ubiquitous within mammalian genomes, and long single-molecule reads produced by third-generation …
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Using post-genomics technologies to advance understanding of liver fluke therapeutics
… analysis of a new Fasciola hepatica genomic resource and the application of RNA interference (RNAi) methodology, to investigate diverse aspects of liver fluke biology. In particular, new data on the diversity and expression of liver fluke ABC transporters has revealed previously …
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Gillenia trifoliata: a tool to understand the genetic regulation of apple flesh development
… as a negative control. Firstly, phenological and genomic resources were established for Gillenia (Ireland, Wu, et al., 2021), and together provide an interspecies standardisation tool and genomic resource for comparative analyses. Genome-wide analysis of select gene families revealed conserved …
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Expanding Genetic and Genomic Resources for Sex Separation and Mosquito Control Strategies
… for Anopheles albimanus. The utility of this genomic resource is demonstrated by the discovery of novel telomeric repeats at the ends of the chromosomes that could have important implications in mosquito biology and control. Chapter 3 describes a forward genetics strategy called …
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INVESTIGATION OF RESILIENCE AND ITS GENETICSTHROUGH THE USE OF LONGITUDINAL DATA
… simulation of perturbations, and genomic analysis. The research was motivated by the need to breed animals capable of maintaining productivity amid the environmental and economic challenges facing modern agriculture. Thanks to close collaboration with a medium-large dairy farm in …
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Genomic insights into the evolution of the parasitoid Microctonus aethiopoides
… these gaps, using population and comparative genomic approaches to investigate the adaptability of M. aethiopoides. Chapter 2 is a review that synthesises global research on parasitoid adaptation and identifies knowledge gaps across four key traits i.e., reproductive mode, olfaction, thermal …
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Multi-omics investigation of interactions between persistent bacteria and Salmonella in the inflamed gut
… community setting lack model-specific microbiome resources to accomplish the feat. Presented in this dissertation is a comprehensive catalogue of CBA/J mouse gut microbial genomes created as a resource for the research community. The genome database was used to recruit various omics data types to …