Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 54 for “"Genomic diversity"”.
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GENOMIC DIVERSITY IN Staphylococcus Aureus
… gel electrophoresis (PFGE). Thirty-nine distinct genomic macrorestriction patterns (GPs) were identified using <em>Sma</em>I; 29 of these patterns are from methicillin-resistant <em>S. aureus</em> (MRSA).</p> <p>A dendrogram showing percent similarity among the patterns was constructed which …
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Genomic diversity of Lactobacillus salivarius
… to have an understanding of the level of genomic diversity present in this species. Comparative genomic hybridization (CGH) and multilocus sequence typing (MLST) were employed to assess the level of genomic diversity in L. salivarius. The wellcharacterised probiotic strains L. salivarius …
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Genomic diversity in naturally transformable Streptococcus pneumoniae
… capsular switching, all reflect the extensive diversity and plasticity of the genome of this naturally transformable organism which can readily alter its genome in response to its environment and the pressures placed upon it in order to survive. The purpose of this thesis is to investigate this …
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Quantifying genomic diversity and growth in Iowa bluegill
1 PDF file (vi, 44 pages)
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Genomic diversity and genomic typing of Salmonella enterica serovar Typhimurium
Salmonella enterica serovar Typhimurium (S. Typhimurium) is one of the most frequently reported serovars in Australia. In the first study of this thesis, 21 S. Typhimurium genomes from Salmonella reference collection A (SARA) were sequenced. Together with 47 publicly available S. Typhimurium …
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Genomic Diversity of Magnetotactic Bacteria from Underexplored Extreme Aquatic Habitats
… and marine sediments, our understanding of their diversity, ecological function, and evolutionary significance in extreme and underexplored habitats remains limited. This doctoral research addresses these knowledge gaps by investigating MTB in two ecologically and geochemically distinct systems: …
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Genomic Diversity of Magnetotactic Bacteria from Underexplored Extreme Aquatic Habitats
… and marine sediments, our understanding of their diversity, ecological function, and evolutionary significance in extreme and underexplored habitats remains limited. This doctoral research addresses these knowledge gaps by investigating MTB in two ecologically and geochemically distinct systems: …
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Genomic diversity and structure among South and East Asian human populations
… region to study human population genetic diversity and population structure. From animal studies, colonization of islands is often associated with loss of genetic diversity resulting in isolation. Although humans can easily move around, various aspects could result in isolation between …
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Comparative analysis of Cronobactor sp. with respect to genomic diversity and physiology
… pESA2 (31 kb) and pESA3 (131 kb). Comparative genomic hybridization (CGH) was undertaken on five C. sakazakii strains, and representatives of four other Cronobacter species. CGH highlighted 15 clusters of genes that were divergent or absent in more than half of the tested strains.
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Genomic diversity and antimicrobial resistance in Salmonella isolates recovered from diverse sources in Nigeria
… is that a better understanding of the genetic diversity, and sources, of antibiotic resistant Salmonella spp in Nigeria, and of markers of emergent antibiotic resistance will inform and encourage the development of integrated interventions to reduce the impact of Salmonella in this country. …
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An Assessment of Caribou (Rangifer tarandus) Genomic Diversity and Structure in Western Canada to Guide Species Conservation and Management
… one of the biggest threats to global biological diversity, and the resulting environmental conditions have made it increasingly difficult for species to adapt and survive. The use of genomic technologies, such as the inference of genetic structure, can aid species conservation and prevent …
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Array-based genomic diversity measures portray Mus musculus phylogenetic and genealogical relationships, and detect genetic variation among C57Bl/6J mice and between tissues of the same mouse
Mouse models lack affordable genomic technologies slowing the identification of candidate variants contributing to complex phenotypes. The Mouse Diversity Genotyping Array (MDGA) is a low cost, high-resolution platform permitting genomic diversity assessment. Using a validated list of >500,000 …
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A preliminary analysis of the lipid contents of a biofilm from a Yellowstone hydrothermal pool
… Most of the previous studies focused on the genomic diversity of these environments, but recent interest in environmental samples for the study of lipid biomarkers has extended to these hot springs as well. In this preliminary study of Obsidian Pool, I used a modified Bligh and Dyer …
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Prevotella Phylogeny: Genomic And Molecular Insights Into The Role Of The Human Commensal Prevotella In Cystic Fibrosis
… Prevotella remains understudied both at the genomic and phenotypic levels. In this thesis, we explore the role of Prevotella in the context of the cystic fibrosis lung microbiome. In this thesis we characterize the ecological composition of a longitudinal pediatric CF cohort called EcoCF and …
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Comparative Genomics of Selected Species of Gram-Negative Bacteria
Investigation of genomic diversity can provide insight into the evolutionary history of bacterial species. However, complete genome sequencing is not yet practical for large strain collections at the beginning of this project. In this project PCR-based methods to investigate the genomic diversity …
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Virtual microfluidics : a novel single-cell technology based on diffusion-restricted reaction that makes high-quality low-input genomic research accessible
The extensive genomic diversity of complex systems, such as the human gut microbiome and the evolution of human cancer, has been revealed with advances in DNA sequencing. But we are still at an early stage in understanding this genomic diversity to expand our knowledge in biology and for biomedical …
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Molecular ecology and fitness of striped (Stenella coeruleoalba, Meyen, 1833) and common (Delphinus delphis, Linnaeus, 1758) dolphins
… dolphin, using molecular methods regarding the genomic diversity and parasite resistance. The striped and the common dolphin have a world-wide distribution, inhabiting pelagic waters and differ with respect to population structure within the study area. The aim is to reveal different patterns of …
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Exploring the Polyclonal Antibody Responses Induced by Klebsiella pneumoniae Derived Outer-Membrane Vesicles
… Klebsiella pneumoniae stands out due to its vast genomic diversity with only a small percentage of the genome being dedicated to the core genes, while the remainder is drawn from a diverse pan-genome. K. pneumoniae can cause a wide range of pathologies including pneumonia, sepsis, urinary tract …
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Population structure of the lizard Ecpleopus gaudichaudii coincides with a biogeographic barrier - the Doce River
… of diversification and the accumulation of biodiversity. The degree to which isolated populations of the same species are genetically structured in geographical space is impacted by a variety of mechanisms. In this study, I document patterns and discuss possible drivers of genetic structure …
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Development of next-generation optical neural silencers
… opsins through an exploration of ecological and genomic diversity, and further boosted opsin function and trafficking through the appendage of signal sequences. The green-light drivable archaerhodopsin-3 (Arch) from Halorubrum sodomense and the yellow-light drivable archaerhodopsin from …
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