Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Genomic Risk"”.
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Lipidomic Dysregulation in Alzheimer's Disease: Relation to Genetics, Neuroimaging and Other Biomarkers
… disease (AD) have identified more than 20 risk loci and several pathways including lipid metabolism. Lipids are fundamental to cellular structure and organization, where they compose biological bilayer membranes surrounding the cell. In their structural role, lipids provide a scaffold for …
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Discovery And Visual Analysis of Tracts of Homozygosity In The Human Genome
I propose a new visual analytics system designed for genetic researchers to study genome-wide homozygosity regions. Finding significant tracts of homozygosity (TOH) using single nucleotide polymorphisms (SNPs) from a large-scale genome data set can contribute to the discovery of genetic factors …
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Functional Drivers of Therapeutic Response in Diffuse Large B Cell Lymphoma
… safe therapeutics, we must first perform deep genomic characterization of the disease to understand its true heterogeneity. We can then study those genes and pathways with genomic alteration and evaluate their effects on the disease. Using this information, we can develop relevant drug …