Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Genomic Aberration"”.
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A genetic screen for genes involved in dendrite morphogenesis of central neurons in Drosophila melanogaster
… neurons can be made homozygous for a defined genomic aberration in an otherwise wild-type (heterozygous) background and visualised during early larval stages. In addition, 85 defined chromosomal deficiencies were recombined individually onto FRT-carrying chromosomes to be screened for genes …
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NOVEL THERAPEUTIC STRATEGIES IN LUNG CANCERSTRONG BIOLOGICAL BIAS FOR ALK INTRON 19 BREAKPOINTS IN NON-SMALL LUNG CANCER
… rearrangements represent one of the most common genomic aberration in cancer and chromosomal translocation that lead to oncogenic kinase activation are observed in many solid tumors. These tumors express activated fusion kinases that drive the initiation and progression of the malignancy. In the …
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Genomic aberrations as determinants of immune infiltrates in high grade serous ovarian carcinoma
… tumourigenesis leave imprints of copy-number aberrations (CNA) in the patient’s genome. These CNA can be summarised into seven copy number (CN) signatures, each associated with a specific mutational process. To identify mutational process associated with determining the immune response to …