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Showing 1 to 2 of 2 for “"Genome Wise Association Studies"”.
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New Score Tests for Genetic Linkage Analysis in a Likelihood Framework
… mainly using unrelated case-control data, i.e., genome-wise association studies (GWAS). However, the emerging availability of sequencing data and the inability to detect rare risk variants by GWAS has led to a renewed interest in linkage and other family-basedmethods.</p><p>Olson (1999)’s …
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Novel Machine Learning Models for Identification, Characterization and Prioritization of Phenotype-Genotype Associations
… problems caused by phenotype heterogeneity in association studies of complex traits. Many complex diseases, such as autism, diabetes and cancer, are very heterogeneous in terms of the realized phenotypes, i.e. individuals diagnosed with the same disease might experience substantially different …