Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Genome, Viral"”.
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Computational Methods for Haplotype-aware De Novo Genome Assembly from Long Reads
Genomes of the same species usually show high diversity due to genetic variations. Most eukaryotes involve multiple copies of genomes, each of which is inherited from one of the ancestors. Whereas prokaryotes, such as virus and bacteria, are prone to form a collection of closely related strains …
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The Tradeoffs for a Viral Mutant with Enhanced Replication Speed
… speed. We found that a single mutation in a viral capsid protein, VP1-F106L, was sufficient for the fast-replication phenotype. Characterization of this mutant revealed quicker genome release during entry compared to wild-type virus, highlighting a previously unappreciated infection barrier. …
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The Association of the Human Cytomegalovirus Genome with the Cellular Nuclear Matrix
… infection. In addition, other regions of the viral genome bound the in situ nuclear scaffold at these times post infection.</p> <p>A reporter gene construct driven by the full length MIE regulatory region and a construct from which an upstream portion of regulatory region was deleted, were …