Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Genetics Research"”.
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Forensic genetic research on sudden unexpected death in an infant (SUDI) at Salt River Mortuary: experiences an perceptions of parents
… of participating in molecular autopsy research are unknown, and not previously done in South Africa. This study explored the experiences and perceptions of bereaved next-of-kin participating in forensic genetic research on SUDI at Salt River Mortuary, Cape Town. Methods Eleven …
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The New Borderland: A Mixed-Methods Examination of Teacher Perceptions of Intelligence, Race, and Socioeconomic Status in Relation to Behavior Genetics
Behavior genetics argues intelligence and educational attainment are highly heritable (genetically influenced) and polygenic (influenced by many genes) traits. Researchers in this field have moved beyond identifying whether and how much genes influence the manifestation of a given outcome to trying …
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Covalent end-immobilization of oligonucleotides onto solid surfaces
… of the Human Genome Project, the focus of genetics research has shifted towards functional genomics, with emphasis on gene expression and polymorphism studies. To this end, there is rapidly increasing interest in solid-phase, high-throughput, combinatorial microarrays for DNA assays. For …
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Laying the Foundation in Genetic Medicine: Understanding Why African Americans and Hispanic/Latinos are Underrepresented in Genetic Testing and in Genetic Research
… when it comes to participating in medical genetics research opportunities and also in genetic testing (Shavers, Lynch, & Burmeister, 2002). Lack of participation among African-American individuals can attributed to mistrust, due to past misuse in clinical research settings such as the …
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Bayesian Hidden Markov Models for finding DNA Copy Number Changes from SNP Genotyping Arrays
… segments of the genome, have become a focus of genetics research. This dissertation develops Bayesian HMMs for finding CNVs from single nucleotide polymorphism (SNP) arrays. A Bayesian framework to reconstruct the DNA copy number sequence from the observed sequence of SNP array measurements is …
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Improving Clinical Risk Models through Integration of Polygenic Risk Scores and Omics
… and diseases, leading to breakthroughs in human genetics research. However, interpretation of these results is often difficult as the GWAS-identified variants (single-nucleotide polymorphisms [SNPs]) often have small effect estimates on target traits, limiting their direct application to disease …
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The Genetic Epidemiology of Purging Disorder, Anorexia Nervosa, and Obsessive Compulsive Personality Disorder
… influence how these disorders are recognized, researched, and treated. This dissertation included two studies addressing important questions within the fields of eating disorders and genetics; specifically, Study 1 addressed the prevalence and heritability of purging and purging disorder in a …
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Genetics-based research at the Minnesota State Fair: the impacts of public engagement on participatory experience
… ethical, legal and social implications (ELSI) of research have become immersed in genetics-based research discourse. While STEM education rates are decreasing in the United States and public opinion of genetics-based research remains somewhat divided, it is important to assess ways in which the …
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High-Throughput Phenotyping for Soybean Iron Deficiency Chlorosis Using an Unmanned Aircraft System: Applications in Breeding, Agronomy, and Genetics
… that UAS estimates of IDC are useful in soybean genetics research programs. In addition, novel QTL were identified for the rate of IDC recovery. Overall, the efficiency and precision of UAS-based image analysis of IDC can be useful in breeding, agronomic, and genome-wide association studies.
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Dissecting Transcriptional Regulatory Networks with Systems Biology Approaches
… and mechanisms of gene regulation. This thesis research is focused on understanding these mechanisms of transcriptional regulation using systems biology approaches. Transcription regulatory networks play an important role in mediating external stimuli and coordinating responses to changing …
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Genetic differences in lung adenocarcinoma cells from patients of African and European ancestry
In the past two decades, advancements in cancer genetics research have significantly enhanced our molecular comprehension of human cancers. This progress has led to the development of improved clinical tools for the precise diagnosis, prognosis prediction, and tailored treatment of cancers. …
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Genomic Designation: New kinds of people at the intersection of genetics, medicine and social action
Genetics can do more than predict, explain or help treat medical conditions - it can create new ones. The social sciences have assumed that genetics must work in and through existing categories of human difference in order to inform clinical practice or social mobilization. By contrast, I go beyond …
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The genetics of non-syndromic hearing impairment in South Africa
… review, we investigated the state of HI research in South Africa was established. Though studies have been performed since the 1960s, the results showed that genetics of HI in South Africa was not well explored. Universal new-born hearing screening is ideal in detecting congenital HI, but …
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Archaeology, archaeogenetics, and identity genetic research within the Maltese context
… – and amongst the most consequential – archaeogenetics can also contribute to politics. Indeed, archaeogenetic discoveries are adding a new dimension to questions of identity. The close relationship between archaeogenetics and identity is attested by the vast amounts of studies that are being …
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Hybridization in Ants
… how these two phenomena are related, and more research is needed to answer this question. As a first step in answering these questions, I designed a set of microsatellite markers for use in African driver ants in the genus Dorylus. Additionally, to facilitate population genetics research in all …
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