Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 170 for “"Genetic variability"”.
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Genetic variability and cadmium metabolism and toxicity
… (toxicodynamics) of Cd. This may be due to genetic factors. The aim of this thesis was to identify genetic factors that are associated with Cd metabolism and toxicity. As Cd is a foreign element, there is no endogenous metabolism of uptake. However, there is evidence that the transporters of …
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TNFRSF13B Genetic variability an anthropological - evolutionary approach to Biomedical Research
… coding variants have been implicated by clinical genetics studies in Common Variable Immunodeficiency (CVID), the most common clinically relevant primary immunodeficiency in individuals of European ancestry, but their functional effects in relation to the development of the disease have not been …
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Bioinformatic methods for the analysis of genetic variability and regulation
… data to address questions related to how cell's genetic and epigenetic makeups give rise to phenotypic traits and regulatory processes. We started analyzing the relationship between genetic information and phenotype. On one hand, we used DNA-seq to compare the genomes of two behaviorally …
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Population Structure, Aggressiveness, and Molecular Genetic Variability of Sclerotinia Sclerotiorum
… structure, isolate aggressiveness, and molecular genetic variability of Sclerotinia sclerotiorum (Lib) de Bary was investigated. Population structure was determined by mycelial compatibility grouping (MCG). MCG and aggressiveness of S. sclerotiorum isolates from diverse hosts and geographic …
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The role of non-genetic variability in Acute Myeloid Leukaemia
… dismal survival. It has a strong reliance on epigenetic and transcriptional factors for disease progression. Accordingly, my lab has previously identified KAT2A, a histone acetyl-transferase, as a requirement for AML maintenance, where chemical inhibition of KAT2A promotes differentiation of AML …
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Genetic variability and differentiation in niche components of marine phytoplankton species
… The data were used to determine the amount of genetic variability and the spatial patterns of genetic differentiation in these species. None of the species examined exist purely as clones in nature. Statistically significant genetic variability is found even among clones isolated from single …
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Amplified fragment length polymorphism (AFLP) analysis of genetic variability in Phalaenopsis
… markers allow a rapid assessment of the level of genetic variation that would be difficult to evaluate using a limited number of morphological markers. AFLP was used to assess the level of genetic variation among 16 different Phalaenopsis species and hybrids. Ten AFLP primer combinations were used …
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Molecular markers for the assessment of genetic variability in threatened plant species
La variabilità genetica è un importante strumento per lo studio e la conservazione della biodiversità in specie rare e minacciate di estinzione. Durante il mio dottorato mi sono quindi occupata di mettere a punto diverse metodologie molecolari al fine di valutare la diversità genetica in due specie …
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Genetic variability, demography, and habitat selection in a reintroduced elk (Cervus elaphus) population
Understanding factors that influence genetic variability, demographic vital rates, and resource selection is important for conservation and management of wildlife populations. I examined factors influencing microsatellite variability, demographic vital rates, and habitat use for a reintroduced elk …
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Genetic variability in Douglas-fir based on molecular genetic markers and morphological traits
Genetic variability in Douglas-fir (Pseudotsuga menziesii (Mirb) Franco) in British Columbia was assessed both by analyzing molecular genetic markers at the population level and by evaluation of quantitative traits in parent trees. Genetic variability in the natural populations of Douglas-fir in …
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Expanding the genetic variability of flatpea using tissue culture, mutagenesis, and intercrossing techniques
… animals, including rats and poultry. To increase genetic variability in foliar DABA content and other traits of interest, three approaches were utilized: (1) regeneration of flatpea plants from tissue culture to produce potential somaclonal variants, (2) seed irradiation and screening of …
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Demographic and genetic variability in Cape Dwarf Chameleons, Bradypodion pumilum, withink a fragmented, urban habitat
… often investigate population demography and genetic variability for species inhabiting fragmented landscapes. Findings from such work enable effective conservation management, maximizing viability for potentially imperiled populations. Previous research has relied predominately on spatial …
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Genetic Variability of Growth and Development in Response to Nitrogen in Two Soft Winter Wheat Populations
… in wheat, with emphasis on breeding efforts and genetic resources available to increase NUE. The concept of effective use of nitrogen (EUN) as yield per unit N applied as a measure of N use, is also introduced. Chapter II is a study using two bi-parental double haploid families to evaluate …
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Genetic Variability, Correlations and Selection Response for Kernel Traits in Two Modified Endosperm Opaque-2 Maize Populations
To determine the genetics of endosperm modification and the relationships with other traits in opaque-2 (o(,2)) maize (Zea mays L.), an investigation was conducted to estimate genetic variation, correlations and responses to S(,1) family selection for kernel traits in two modified endosperm o(,2) …
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Genetic Variability, Pathogen Susceptibility, Subspecies Identity and Conservation of the Endangered Northern Flying Squirrel (Glaucomys sabrinus) in Virginia
I examined the population genetic structure of three known subspecies of Glaucomys sabrinus from Appalachia, Washington State, and two previously unexamined populations from Mount Rogers National Recreation Area (MRNRA) in Southwestern Virginia. Mean FST (0.107) and an AMOVA (P G. sabrinus …
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Impact of genetic variability in the serotonin transporter, Tryptophan Hydroxylase-2, and Serotonin 2A Receptors on MDMA Use and Impulsivity
Ecstasy [MDMA; (±)-3,4-methylenedioxymethamphetamine] is popular for positive effects including enhanced mood and empathy, despite potential deleterious physical and psychological consequences. The serotonin (5-HT) system plays a prominent role in the neurochemical and behavioral effects of MDMA, …
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