Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 265 for “"Genetic studies"”.
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Genetic studies with Bordetella pertussis
Summary available: p.18
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Genetic studies of cardiometabolic traits
… interaction between an individual’s predisposing genetic makeup and a permissive environment. Since 2007, genome-wide association studies (GWAS) have been successfully applied to complex traits leading to the discovery of thousands of trait-associated variants. Nonetheless, much is still to be …
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Genetic studies on Clostridium acetobutylicum
… acetobutylicum and the development of a genetic transfer system for this organism. The production of a carboxymethyl cellulose and a cellobiase by C acetobutylicum was demonstrated. In liquid medium the carboxymethyl cellulase was induced by molasses, and it was not repressed by glucose. …
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Developmental genetic studies on Thiobacillus ferrooxidans
… investigation extends current knowledge of the genetics of this organism. Conjugation was attempted as a means for plasmid DNA transfer to T. ferrooxidans. Recombinant T. ferrooxidans plasmids, pDER401 and pDER405, were shown to code for mobilization and replication functions in Escherichia coli …
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Molecular genetic studies of bacteroides fragilis
Some genetic systems operative in Bacteroides fragilis have been successfully investigated. Firstly the bacteriocin produced by the B.fragilis BF-1 strain was purified and partially characterized. This bacteriocin was found to be cell bound and constitutively produced by the bacteria. The purified …
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Genetic Studies of Psoriasis and Psoriatic Arthritis
… psoriatic arthritis. Both diseases have a strong genetic component but are also affected by environmental factors and are thus regarded as multifactorial. A major genetic factor contributing to susceptibility to both diseases is believed to reside at the HLA locus on chromosome 6, although …
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Clinical and genetic studies in Noonan syndrome
Contains fulltext : 147092.pdf (Publisher’s version ) (Open Access)
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Genetic studies in Sanfilippo syndrome, type B
This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).
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Biochemical And Genetic Studies of Quebec Platelet Disorder
… individuals experience hematuria; and 3) map the genetic locus of QPD, and look for the putative mutation. Studies of clot lysis indicated that QPD platelets induce a gain-of-function defect in fibrinolysis when platelets are incorporated into clots. This suggests that accelerated fibrinolysis may …
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Genetic studies of Streptomyces cattleya and Streptomyces olivaceus
Actinophage VCll is able to virulently infect 11 of the 20 Streptomyces strains tested. Examination of VCll infection of Streptomyces cattleya, Streptomyces olivaceus and Streptomyces lividans TC10 indicated the absence of restriction-modification systems which affect VCll infectivity of these …
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Male Subfertility and Prostate Cancer Risk: Epidemiological and Genetic Studies
… PCa risk; and 3) the possible involvement of genetic variants in reducing PCa risk in subfertile men, including in the sex steroid signaling pathway and aryl hydrocarbon receptor (AHR) pathway, which mediates some of the effects of endocrine disrupting chemicals, and also in PCa risk genes …
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Chemical Genetic Studies of Tumor Suppressors in the Developing Zebrafish
… allow it to be used for high-throughput genetic and chemical screens with high translational potential. One mutant isolated from a screen for cell cycle deficiencies is the zebrafish cdc25a mutant standstill. This mutant suffers from a G2/M arrest due to activation of the checkpoint …
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Biochemical and Genetic Studies of Beclin 1 Function in Autophagy
… and degeneration. In a study that combines mouse genetics and biochemistry, three novel Beclin 1 interaction proteins Atg14L (yeast Atg14-like), Rubicon (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein) and Nrbf2 were identified from mouse tissues. Gel filtration and …
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Genetic studies of mutants of Neurospora crassa lacking ornithine transcarbamylase
Arginine has long been of interest to chemists, biochemists and biologists because of its close relation-ship to urea. Srb and Horowitz (1944) isolated many arginineless mutants of Neurospora crassa and found the mutants confirmed Krebs' claim (1932) that ornithine and citrulline are precursors in …
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Genetic studies of phenotypic variants in the woodland strawberry, (Fragaria vesca)
… This thesis represents some of the first forward genetics studies evaluating putative T-DNA insertional mutants in F. vesca. The observed phenotypes include alterations to floral development, anthocyanin pigmentation and leaf structure. The floral development mutant named green petal (gp) was not …
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