Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 45 for “"Genetic selection"”.
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ReGen: Optimizing Genetic Selection Algorithms for Heterogeneous Computing
<p>GenSel is a genetic selection analysis tool used to determine which genetic markers are informational for a given trait. Performing genetic selection related analyses is a time consuming and computationally expensive task. Due to an expected increase in the number of genotyped individuals, …
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Genetic selection of cyclic peptide G-quadruplex ligands
… manipulation. Moreover, since amino acids are genetically encodable, they naturally lend themselves to biosynthetic, high-throughput selection methodologies, allowing simultaneous analysis and identification from libraries containing millions of different molecules. Two contrasting cyclic …
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TOWARDS AN UNDERSTANDING OF GENETIC SELECTION IN BREAST CANCER
… vitro. We sought evidence in breast cancer that genetic selection acts to maintain tumour survival. Analysis of genomes from 243 breast tumours revealed 766 unstable and 812 stable contiguous genomic regions. Stable DNA targets were confirmed by quantitative PCR in six breast cancer cell lines. …
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Effects of genetic selection and processing of soybeans and soybean meal on nutritional quality
… were conducted to study the effects of genetic selection and processing of soybeans and soybean meal on nutritional quality when fed to pigs. The objectives of Exp. 1 and 2 were to determine standardized ileal digestibility (SID) of AA, and the DE and ME in de-hulled conventional full …
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Shifts in livestock technology, programming, and composition: exploring the future of livestock agriculture
… highlights a change in technology, improved genetics, and estimates the relationship between genetic selection and farm profitability. Genetic selection is measured by net merit, which is an index based on economically relevant traits that ranks U.S dairy cattle based on their expected …
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The Estrogen Response Element and the KRAB Repression Domain as Modulators of Estrogen Receptor Action
… ERE affinity previously identified in a genetic selection, allowed us to effectively repress in a ligand dependent fashion both basal and estrogen receptor induced transcription from a promoter containing a single non consensus ERE. These ER-KRAB chimeras therefore constitute powerful …
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The Influence of Necrotic Enteritis, Environmental Factors, and Genetics on Intestinal Development Pathways and Disease Occurrence in Broiler Chickens
… structure and function, environment, and genetic selection. Chapter 2 investigated the host response to infection of the parasite Eimeria maxima that predisposes chickens to a bacterial infection Clostridium perfringens. Intestinal structure, function, inflammatory response, and epithelial …
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Influence of selection for breast muscle mass on pH and metabolism of supracoracoideus muscle from male and female turkey
The objective of this study was to determine if selection for increased breast muscle mass has affected the supracoracoideus muscle's ability to regulate pH during physical activity in turkeys. The lightweight male line (LM) had the greatest breast muscle mass as a percent of body weight (p < …
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A Multi-GPU Compute Solution for Optimized Genomic Selection Analysis
… compute solution for optimizing GenSel, a genetic selection analysis tool. GenSel utilizes a MCMC algorithm to perform Bayesian inference using Gibbs sampling.</p> <p>Optimizing an MCMC algorithm is a difficult problem because it is inherently sequential, containing a loop carried …
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Morphological and Physiological Responses of Senegalia senegal (L.) Britton Provenances to Drought, Salinity, and Fertility
… trial. In general, results showed a high intra genetic variability of Senegalia senegal on gum yield, biomass accumulation and growth. Ngane provenance presented superior growth characteristics as both mature trees and seedlings and exhibited a more conservative water use strategy under drought. …
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EPIDEMIOLOGY AND POPULATION GENETICS OF THE GRAPE POWDERY MILDEW CAUSAL FUNGUS, ERYSIPHE NECATOR, AND ITS RELATION TO COMMERCIAL DISEASE MANAGEMENT
… sexual stage as chasmothecia. Having a diverse genetic pool and mixed mode of reproduction contributes to a high evolutionary potential to overcome disease management methods; powdery mildews have been shown numerous times to overcome host resistance and several fungicide groups within a couple …
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Bacterial profiles and ex vivo effects of Salmonella Heidelberg on leukocyte function in turkey purebred lines
… prevention, receiving increased attention, is selection to improve genetic resistance. This study evaluated the effects of an oral Salmonella Heidelberg (SH) challenge on bacterial colonization, and the ex vivo effects of SH on phagocytic and bactericidal leukocyte function in turkeys from six …
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In vitro milk protein secretion by explants of Holstein bull mammary tissue from two different genetic lines
… proteins was studied. Sixteen bulls from the genetic selection and control lines developed at Virginia Polyteclmic Institute were randomly assigned to either a non-treated or steroid pretreated group. The steroid pretreated group received estradiol 17-B and progesterone at 0.1 and 0.25 …
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Ruminal Nitrogen Recycling and Nitrogen Efficiency in Lactating Dairy Cattle
… effect of cow on MUN variation may reflect genetic selection decisions of animals with either poor or efficient urea transport. A second trial observed that MUN and PUN concentrations were positively correlated with gut urea clearance, providing evidence for differences in urea transport …
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The effect of selection for milk yield on net energy balance and plasma concentrations of endogenous hormones and metabolites in primiparous Holsteins
The effect of genetic selection for milk yield on lactation yield, net energy balance (NEB) and on plasma growth hormone (GH), insulin (INS), prolactin (PRL), nonesterified fatty acids (NEFA) and glucose was studied in primiparous Holstein cows. Net energy balance was calculated and serial blood …
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The Role of Long Distance Movement and Genetic Adaptation on the Evolution of West Nile virus in the New World
… collected in Texas could be used to identify genetic selection occurring throughout the country. However, sequencing data could not be used to predict virulence as there was no relationship between intra-host variation and phenotype. Finally, the relationship between WNV circulating in North …
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Physical and Biochemical Factors Affecting Breast Fillet Tenderness in Broilers Reared For Divergent Market Demands
… market demands for decades. Also, broiler genetic strains have been adapted to meet market demands which include: genetic selection for improved breast meat, the practice of growing birds to older ages and greater market weights to meet demands, and decreasing postmortem (PM) aging time to …
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Milk fatty acid profiles of Holstein and crossbreds of Holstein, Jersey, Normande, Montbéliarde, and Viking Red Dairy breeds in confinement and pasture-based herds
… impacts of selecting for improved FA production. Genetic selection along with pasture-feeding may improve milk FA for potential niche markets. From 2022 to 2024, milk FA profiles of Holstein and crossbred cows sired by Montbéliarde, Viking Red, and Holstein breeds were evaluated on two commercial …
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Xenophagy in response to gram-positive staphylococcus aureus and gram-negative salmonella enterica sv. typhimurium
… in cells. In addition, in this project, CRISPR genetic selection approaches were developed, aimed to find new host cell genes required for Staphylococcus aureus and Salmonella enterica sv. Typhimurium infection. The results indicated two different roles of autophagy: 1) to provide a protective …
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