Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Genetic recombination."”.
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Genetic Recombination in Pneumococcal Transformation: The Role of Integrity and Heterogeneity of Deoxyribonucleate Molecules, as Reflected in Kinetic Analysis
… has been used to study intramolecular genetic recombination. A kinetic technique is developed whereby the cumulative number of multiply-marked transformants is measured as a function of the duration of exposure to a multiply-marked DNA. Transformants accumulate with time at a rate …
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De novo morphogenesis on tomato thin cell layers and variation for genetic recombination among plantlets regenerated from tissue culture
… cotyledon calli, or micropropagated shoot tips. Genetic recombination rates and map distances were compared among hybrid plants grown in the greenhouse and regenerated from the aforementioned tissue culture systems. Increased recombination rates and map distances were detected between the sunny …
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Population genomics of Sulfolobus islandicus: genome-wide recombination and antagonistic interactions
… organisms that occasionally engage in genetic transfer and recombination. With the onset of the era of genomic sequencing of natural populations of microorganisms, it has been revealed that genetic recombination is not just a useful laboratory tool for microbial geneticists, but instead …
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Characterizing the effect of mutation recombination and reassortment on the genetic diversity of African horse sickness virus genomes
… mutations. The virus could potentially undergo genetic recombination and reassortment during the co-infection of the same host cells by at least two different virus strains of the same species. Since it is an arbovirus, we proposed that the virus would evolve slower than other RNA viruses that …
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Mechanism of regulation of human RAD51 recombinase through post translational modifications & mediator proteins
… protein plays an important role in homologous genetic recombination (HR), an essential DNA metabolic process used by cells to faithfully repair the most deleterious forms of DNA damage and maintain genomic integrity. RAD51 along with its bacterial counterpart RecA, bacteriophage UvsX and …
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EVOLUTIONARY AND MECHANISTIC INTERACTIONS IN VIRUS TRANSMISSION BY APHIDS
… literature review. I used proteomics and aphid genetics to show that the “biotype” phenotype of aphids is generated by genetic recombination in sexual reproduction and that aphid virulence and virus transmission are independent traits. I also showed that the host plant where aphids are reared on …
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Sex, Diversity, and Differentiation Within and Between Populations of an Aquatic Hyphomycete
… of aquatic hyphomycetes to acquire and maintain genetic diversity. Tetracladium marchalianum is used in this study to answer three questions pertaining to the natural histories and evolutionary potential of these ecologically important fungi. (1) Is genetic recombination contributing to genotypic …
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W-reactivation (Inducible "SOS" DNA Repair) of double stranded DNA bacteriophage ? and single stranded DNA bacteriophage fd on isogenic rec and uvrB mutants of Escherichia coli K-12
The recA mutant has been shown to be completely recombination deficient and highly UV-sensitive. Also, this mutant is remarkably deficient in inducible "SOS" DNA repair and, consequently it is not UV-mutable and it cannot perform W-reactivation, an inducible non-excision repair dependent …
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Genetic diversity and taxonomical relationships among the tacaribe serocomplex viruses (family arenaviridae)
… Arenaviridae), 2) extend our knowledge of the genetic diversity of the Tacaribe serocomplex viruses, and 3) establish genetic criteria for species demarcation within the Arenaviridae. Study 1 -- The results indicated that Neotoma macrotis (large-eared woodrat) is the principal host of Bear …
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Non-parental-type Recombinants in Crosses between Different Restriction-Modification Systems in SALMONELLA
… of DNA. Recent experiments have indicated that genetic recombination is initiated at the end of single-stranded pieces of DNA, (Hollman, Wiegand, Hoessli, and Radding, 1975). This could help to explain the high frequency of transduction of the "zero" phenotype.</p>
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The evolutionary impacts of secondary structures within genomes of eukaryote-infecting single-stranded DNA viruses
… of natural selection, sequence co-evolution, and genetic recombination, it is possible to both validate the existence of, and infer the biological importance of, computationally predicted structures. Here I implement and deploy free bioinformatics tools to (1) automate nucleotide and protein …
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Maternal environment and offspring physiology : the inheritance of information across a generation
… evolutionary synthesis, which postulates that genetic and phenotypic variability in plant and animal populations are brought about by genetic recombination resulting from sexual reproduction and random mutations. Nonetheless, throughout the 20th century there have been several observations of …
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Fibroblasts: Key Cells in Inflammation and Fibrosis
… with tamoxifen (Col1a2-CreERT), undergo targeted genetic recombination in aortic fibroblasts. Using mT/mG Cre-reporter mice harboring Col1a2-CreERT, I provide evidence that Col1a2-CreERT is activated by tamoxifen in both adventitial fibroblasts and in vascular smooth muscle cells (VSMCs). …
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The ecology of Bacillus thuringiensis on the phylloplane
… stains, which was activated by the process of genetic recombination, was isolated and characterized. The appearance of naturally occurring strains of B. thuringiensis in vegetative and spore form was followed over a growing season on clover (Trifolium hybridum) in the field. Simultaneous and …
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Genomic epidemiology of oat crown rust disease in Australia and abroad uncovers diverse mechanisms to generate diversity
… two individuals exchange entire nuclei without recombination (nuclear exchange). However, it is not understood how much these three mechanisms may contribute to host adaptation at a population scale in most rust species. A pathosystem which is well-suited to explore this is Puccinia coronata f. …
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Genomic epidemiology of oat crown rust disease in Australia and abroad uncovers diverse mechanisms to generate diversity
… two individuals exchange entire nuclei without recombination (nuclear exchange). However, it is not understood how much these three mechanisms may contribute to host adaptation at a population scale in most rust species. A pathosystem which is well-suited to explore this is Puccinia coronata f. …
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Toward a Restoration Protocol for Mediterranean Red Coral: Incorporating Life History Traits, Genetics, Demography, and Experimental Approaches
… populations that are demographically stable and genetically resilient, ensuring their long-term viability and adaptability to future environmental changes. To this aim, I focused on two key aspects: (1) demography, trying to decode reproduction mechanisms (Chapter 1), and better describe the …
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Models and methods for computer simulations as a resource in plant breeding
… models of the genome and the process of genetic transmission through generations, the breeding process, and other ‘processes’ involved in genetic recombination, identification and production of new cultivars. Additionally, the statistical methodology employed has ramifications for …
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Static and Microfluidic Live Imaging Studies of Plasmodium falciparum Invasion Phenotypes
… microscopy. Furthermore, to better understand genetic recombination affecting erythrocyte invasion phenotypes, progeny from the 7G8 x GB4 cross was compared to their parents. In order to investigate specific receptor-ligand interactions and their distinct functional characterisations at each …
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Safer without Sex?
… queenright and queenless condition. In the phylogenetically primitive subfamily Ponerinae reproductive caste dimorphism is much less pronounced: Ovarian morphology is rather similar in queens and workers, which additionally retain a spermatheca. In many ponerine species workers mate and may have …
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