Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 197 for “"Genetic material"”.
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Mechanisms of regulation of the spindle position checkpoint kinase, Kin4
… progenitor, requires equal distribution of the genetic material to the two progeny cells. When polarized cells divide, an additional constraint on the segregation of the genetic material is imposed, namely, cells must divide the genetic material along axes defined by polarization cues. In …
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Understanding the Position of the Savior Sibling: How Can We Save Lives and Protect Savior Siblings?
… for creating and using savior siblings as genetic material donors. In the past twenty years, use of savior siblings has increased when living donors cannot be located. Traditionally, a savior sibling is a child conceived to provide transplantable genetic material needed by another sibling. …
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Lethal alleles in wild population of Mus musculus (house mice)
… in Virginia and to report on the nature of the genetic material located at a specific point on the ninth chromosomal linkage group in this species.
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Genomic Justice: The Distribution of Human Flourishing
… for human dignity and public interest. Genes and genetic material (DNA strands of nucleotides, genetically altered plants and animals e.g., see Appendix B) are patentable. In the US and around the globe, governments grant genetic patents for new, non-obvious, and useful gene inventions. A wide …
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Using otolith shape and DNA to identify the stock structure of the spotted wolffish (Anarhichas minor) around Iceland
… minor) inhabit the waters of Iceland, genetic samples and otoliths were collected during the annual spring survey of the Icelandic Marine and Freshwater Research Institute in 2022. Genetic and otolith samples were collected from 185 individuals from Iceland’s West, North, and East …
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Mitigating security issues in the evolving DNA synthesis industry
… methods of synthesis used to create beneficial genetic material can also be used to construct dangerous pathogens. To prevent unknown actors from ordering potentially dangerous genetic material, the largest DNA synthesis firms formed two industry associations that require members to screen the …
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Dynamic properties of the constitutive centromere associated network of proteins
Ensuring the proper transmission of genetic material across generations is fundamental to the propagation of cellular life. In each mitotic cell division, a series of highly regulated processes ensure that the genetic material of a dividing cell is properly duplicated and segregated to produce two …
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Assessing the genetic diversity and structure of spotted hyena (Crocuta Crocuta) populations across Africa
… majestic species. This study aims to address the genetic diversity, population structure and gene flow of these species across different regions of the sub-Saharan distribution. 55 whole genome and restriction site-associated sequences were analysed using Heterozygosity, PCA analysis, Admixture …
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Are Mussel Shells Environmental DNA Time Capsules? A Comparison Of Extraction Methods For Obtaining DNA From Shell Material.
… date (1984-2015) were used as the source of genetic material for this study. Additionally, collection date was tested for influence on the total DNA yield. An interaction between collection year and extraction method was also explored. A total of 40 hinge ligaments were removed from dried …
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Strategies for Enhanced Genetic Analysis of Trace DNA from Touch DNA Evidence and Household Dust
… casework it is often necessary to obtain genetic profiles from crime scene samples that contain increasingly smaller amounts of genetic material, called Low Template DNA (LTDNA). Two examples of LTDNA sources are touch DNA evidence and dust bunnies. Touch DNA refers to DNA that is left …
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Clamp loading on the leading strand during DNA replication and initial reconstitution of sister chromatid cohesion establishment
Accurate and efficient replication of genetic material is essential to all life, with dysregulation of this vital process resulting in genomic instability and disease. In eukaryotes this process is performed by the replisome, a complex protein machinery composed of a core helicase, DNA polymerases, …
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Dewdrops on the genome : regulation of gene expression by biomolecular phase separation
… Each cell-type contains an identical copy of the genetic material yet performs specialized and diverse functions, in large part, due to the selective expression of particular coding DNA-elements (genes) into RNA. Mutations or dysregulation in control of gene expression underlie many diseased …
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Subtraktiver Vergleich der Differenzierungsmuster menschlicher invasiver Trophoblastzellen und maligner Choriokarzinomzellen mit Hilfe von Choriokarzinom-, Trophoblast-Hybriden
… addition they showed that the cell lines contain genetic material from the one parental cell line AC1-1 and additional genetic material most likely from the other parental cell line, the extravillous cytotrophoblast. Moreover the clonal identity of the cell lines could be verified with the help of …
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ROLE OF GENOMIC COPY NUMBER VARIATION IN ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT
… can lead to its earlier diagnosis and treatment. Genetic variation plays a key role in the development of AD, but not all genetic factors associated with the disease have been identified. Copy number variants (CNVs), a form of genetic variation, are DNA regions that have added genetic material …
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Programming of the paternal nucleus for embryonic development
… sperm has been considered merely as a carrier of genetic material at fertilisation. However, it is known that sperm supports embryonic development better than other cell types, suggesting that it might also have additional important, non-genetic contributions to embryonic development. The work …
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Nuclear Encoded Proteins Important in Mitochondrial Genome Stability
… Similar to the nucleus, mitochondria house genetic material (mtDNA), which is responsible for the production of proteins essential to mechanisms required for cellular respiration. Furthermore, if there is a mutation or deletion in the mtDNA there can be ramifications in terms of energy …
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An Analysis of Morphogenetic Movements on the Marginal Indentations of the Chick Embryo Yolk Sac
… may involve mass, cell numbers, cell size, genetic material, or a combination of these. However, the developing organism is not merely composed of more cells or larger cells, but also of several kinds of cells, cells which are different both in structure and function. This variation among …
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Use of RFLP markers in maize as an aid in selection during inbreeding
… markers can be used to detect alleles in donor genetic material for improvement of existing cultivars or hybrids. Restriction fragment length polymorphisms (RFLPs) were used as markers to detect favorable quantitative trait alleles in the maize (Zea mays L.) population BS11(FR)C7 which were not …
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Engineered red blood cells and their applications
… availability in vivo and the ability to genetically modify precursor cells without worry of the terminally differentiated progeny carrying any foreign genetic material. The first part of this thesis is devoted to the establishment of methodologies that allow for the covalent attachment of …
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Survivorship of ploidy-variable unisexual <i>ambystoma</i> aalamanders across developmental stages
… through kleptogenesis, persisting by stealing genetic material from males of compatible bisexual <em>Ambystoma</em> species (e.g., Jefferson's Salamander <em>A. jeffersonianum</em>, and the Blue-Spotted Salamander <em>A. laterale</em>). Kleptogenesis can result in ploidy-variable embryos within …
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