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Showing 1 to 1 of 1 for “"Genetic engineering mouse models"”.
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Immune Landscape of early liver metastatic lesions in a Novel Immunocompetent Murine Colorectal Cancer Metastasis Model
… of disease. In our study, we simulated MRD using genetically engineered organoids with precise somatic editing of APC and TP53, creating a murine model that mimics human liver metastatic colorectal cancer. By implementing a meticulously timed experimental metastatic model, we could detect …