Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Genetic devices"”.
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Engineering Robust and Programmable Biological Systems
… architecture and increasing the complexity of genetic networks. We further demonstrate that increasing demand for cellular resources causes resource-associated interference among noninteracting genetic devices of various complexities. Importantly, we show that feedback systems can be engineered …
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Tools and reference standards supporting the engineering and evolution of synthetic biological systems
… desired products. However, very few of these genetically-encoded systems worked as originally designed. The typical process of constructing a functional system involves a period of tuning the system properties to find a functional variant. This tuning process has been optimized and applied …
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RNA-level controllers for programmable gene expression in mammalian cells
… in synthetic biology, there remains a need for genetic devices that allow for precise control over endogenously and exogenously expressed genes. Here, through two examples, we demonstrate that RNA is well-suited for engineering compact, programmable biomolecular tools with sense and actuate …
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Gene expression control and antimicrobial peptide production by haute couture bacteria
… and homology modeling. Next, the molecular devices were built and tested experimentally.Finally, both systems were characterized using stochastic models of gene expression. Prokaryotic-TetOn and prokaryotic-TetOff are the first prokaryotic devices of their kind, inducible synthetic …