Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 12 of 12 for “"Genetic Toolkit"”.
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Developing a genetic toolkit for plant-parasitic nematodes
… describes and discusses efforts to expand the genetic toolkit for the plant- and nematode-side of the interaction to accelerate the study of the pathology as a whole. The thesis is principally focused on the model cyst nematode *Heterodera schachtii* due to its ability to parasitise the model …
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Expanding the Genetic Toolkit of Fusobacterium nucleatum by Generation of Fully-Sequenced Genomes and Discovery of Natural Competence
… in knowledge can be attributed to the absence of genetic tools and resources to investigate and study host-pathogen interactions of Fusobacterium. Progress in dissecting the role of Fusobacterium in disease has been hindered by a lack of fully sequenced and annotated genomes, and the absence of …
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Circuit Mechanisms of Context-dependent Memory-based Action Selection
… et al., 2015; Takagi et al., 2017), extensive genetic toolkit (Jenett et al., 2012; Kvon et al., 2014; Lai & Lee, 2006; Owald et al., 2015) and fully reconstructed brain connectome (Winding et al., 2024) which includes the MB (Eichler et al., 2017). In this thesis, I demonstrate that aversive …
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Exploring circadian rhythms, food intake, and their interactions in marine invertebrates
… distinct dietary strategies partially share a genetic toolkit to respond to starvation, whereas differences in their starvation responses may reflect different modes of lipid storage. I also use evolutionary analyses to show that starvation response genes are under selective constraint, …
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Comparative Physiological and Genomic Analyses of Division of Labor in Honey Bees and Paper Wasps
… sociality and hint at the existence of a shared genetic ""toolkit"" for the evolution of social organization."
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Nutritional status influences behavior, physiology, and brain gene expression in primitively eusocial Polistes metricus paper wasps
… data provide further support for the idea of a “genetic toolkit” for eusocial behavior because novel regulation of these conserved genes contributes to new forms of related behaviors. The results of this study demonstrate that nutrition has an important role in Polistes metricus paper wasps at …
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Exploring circadian rhythms, food intake, and their interactions in marine invertebrates
… distinct dietary strategies partially share a genetic toolkit to respond to starvation, whereas differences in their starvation responses may reflect different modes of lipid storage. I also use evolutionary analyses to show that starvation response genes are under selective constraint, …
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Genetic dissection of circuits underlying the modular structure of the Superior Colliculus
… of the SC remains elusive is the lack of genetic characterization of the neuronal populations of the motor SC. Here, we performed RNAseq to screen for genetic markers for neuronal subpopulations in the motor SC. We identified a transcription factor, Pitx2, which is exclusively expressed in …
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Decoding novel virulence strategies in Fusobacterium invasion and survival
… that most Fusobacterium species exhibit genetic recalcitrance, which has led to hindrance in the understanding of their biology and molecular pathogenesis. Though the association of Fusobacterium in diseases is well-established, the majority of our experimental work stems from the strain …
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Mechanisms governing transposable element expression in the Drosophila germ line
… of candidate regulatory proteins, and devising a genetic toolkit based on the dead-Cas9 system to definitively test the role of different factors on P-element splicing regulation in vivo. This led me to dissect the relationship between transcriptional start site and splicing regulation, as well as …
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Computational tools for engineering functionally improved genetic components and cellular factories
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-08-01
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New Insights into the Regulatory Network Controlling Neuroblast Migration in C. elegans
… Therefore it is worthwhile to study the genetic mechanisms that control migrating neuroblasts.The model organism Caenorhabditis elegans provides a strong model to study migrating neuroblasts. C. elegans have a complete nervous system containing 302 neurons and an extensive genetic toolkit …