Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"Genetic Predisposition to Disease"”.
-
Investigation of Rare Genetic Variation in Autism Spectrum Disorder by Genomic Screens
… ASD is highly heritable, however known genetic factors that contribute to ASD explain ~30% of cases, with each factor contributing to <1% of cases. The genetic and phenotypic heterogeneity of ASD reduces the power to identify causative genes. Furthermore, even with the growing number of …
-
Analysis of Coding Region SNPs and Its Propensity to Cause Disease
… These variations in individuals are considered to be the cause of diseases, difference in response to treatment, susceptibility to diseases or may have no impact. Association studies aim at correlating an observed disease or a phenotype with these sequence variations. However very few of these …
-
A Mutation in Alk6b Causes Impaired Germ Cell Differentation and Testicular Germ Cell Tumors in Zebrafish
… exhibit differentiated and undifferentiated histologies, which vary in their malignant potential and response to treatment. The pathways that determine tumor cell differentiation are not known, impeding the development of new therapies. Thus, the treatment of GCTs has remained static since the …
-
Neural Mechanisms and Behaviors in Models of Conditional Nprl2 Loss
The file named "DENTEL-PRIMARY-2022-1.pdf" is the primary dissertation file. Two (2) supplemental video files are also available and may be viewed individually.