Global ETD Search
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Showing 1 to 1 of 1 for “"Genes, nef"”.
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Structural and Functional Analysis of HIV-1 Nef Activation of PAK-2
Nef is an accessory protein encoded by HIV-1 that activates the host cellular p21 activated protein kinase 2 (PAK-2). Previous work has characterized the structural plasticity of Nef with regard to PAK-2 activation. Residues 89 and 191 were identified to be components of an effector domain required …