Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Genes, Tumor Suppressor"”.
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Chemical Genetic Studies of Tumor Suppressors in the Developing Zebrafish
The zebrafish is a powerful disease model system. Its distinct advantages allow it to be used for high-throughput genetic and chemical screens with high translational potential. One mutant isolated from a screen for cell cycle deficiencies is the zebrafish cdc25a mutant standstill. This mutant …
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p14ARF : A p53-Independent Tumor Suppressor
… p16 and p14, that play a pivotal role in tumor surveillance.</p> <p>Breakdowns in the p14 pathway have been estimated to be present in approximately 40% of human cancers and only recently have its binding partners and effects begun to be defined. Its interaction with the p53 pathway, which …
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Vaccinia Virus-Mediated Glioma Gene Therapy Using p53, IL-2 and IL-12
<p>Malignant brain tumors are generally lethal soon after their diagnosis, and the five-year survival rate for the patient is low in spite of neurosurgery, radiation therapy, and/or chemotherapy. Gene therapy has the potential to improve patient survival and quality of life by delivering specific …