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Showing 1 to 12 of 12 for “"GeneXpert"”.
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Detection of Genetic Thrombophilia (Fa V Leiden & PT20210 mutation) using GeneXpert Technology with IQCP Implementation
… management.</p> <p>The introduction of the GeneXpert technology by Cepheid will aid in the prevention of staff injury from repetitive motion, improve the turnaround time and eliminate potential risk of error. This test system performs DNA isolation, amplification and detection within a …
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Novel Diagnostic approach for tuberculosis diagnosis
… of a novel rapid diagnostic test for TB, GeneXpert MTB/RIF, in symptomatic adults and to compare it to other commercially available nucleic acid amplification assays and to standard microbiological smear and culture. The GeneXpert system performs real time, nested PCR from sputum and …
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Diagnostic yield of tuberculosis investigations on bone marrow biopsy samples in HIV positive patients at Groote Schuur Hospital
… (TB) culture results may be delayed. The GeneXpert® MTB/RIF Ultra assay may provide a more sensitive diagnostic test on bone marrow biopsy samples. Methods: We conducted a two-stage study in a tertiary hospital in South Africa, initially assessing the retrospective yield of TB diagnoses on …
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Centering Primary Health Care (PHC) Nurses' experiences in their practice of policy implementation - TB diagnostic policy reform in the Western Cape, South Africa
… policy and the implementation of Xpert MTB/RIF (GeneXpert) diagnostic technology into the health system, as a case to assess the extent to which software issues - particularly the human qualities of the system – mediates policy implementation. It centres the experiences of frontline workers in …
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A clinical and molecular analysis of Clostridium difficile strains isolated from Groote Schuur Hospital
… tests (Hain Lifescience CDiff and Cepheid GeneXpert) were far more sensitive in the local clinical setting. PCR ribotyping identified all the A-B+ strains as PCR ribotype 017, which was the prevalent strain type (47%). Genotyping based on the tcdC gene and MLVA both grouped the ribotype 017 …
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Trichomonas vaginalis and bacterial co-infections identified in reproductive age women
… which included Anyplex II STI-7 real-time PCR, GeneXpert CT/NG and GeneXpert TV. The overall prevalence for both clinics of STIs was 13.7% (16/117) and for T. vaginalis specifically, a 10.3% (12/117) rate was observed. A co-infection rate of 2.6% (3/117) was observed in this study. Trichomonas …
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The diagnostic pathway to a surgical lymph node excision biopsy service in a HIV and TB endemic region in a Western Cape Tertiary Institution
… M. tuberculosis were infrequently performed and GeneXpert MTB/RIF assay on FNA never performed. Furthermore, in the seven patients with a final diagnosis of lymphoma in whom FNA cytology was performed, cytology was not diagnostic of lymphoma. In patients with persistent lymphadenopathy, this …
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Relationship between sexual partnerships, intimate partner violence and sexually transmitted infections in pregnant women living with HIV and not living with HIV in Cape Town, South Africa
… vaginalis (TV) using point-of-care PCR testing (GeneXpert, Cepheid, USA). We used multivariable logistic regression to evaluate the association between relationship quality, STI, and IPV during pregnancy, adjusting for maternal age, gestational age and relationship status. Results In 242 pregnant …
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Cytohistologic correlation of suspected Cervicofacial Head & Neck Extra-Pulmonary Tuberculosis in children: A retrospective case series
… Town for evaluation. In addition, results for Genexpert testing and TB culture were identified using the National Health Laboratory Service (NHLS) Trakcare system. In patients that did not have either of the above, MTb PCR testing was performed. Results Data from the reports of 76 children with …
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Επιδημιολογική διερεύνηση λοίμωξης γεννητικού συστήματος από Chlamydia Trachomatis στον Ελλαδικό χώρο την τελευταία τριετία
… με τη real-time PCR(CT/NG test) στο σύστημα GeneXpert(Cepheid) στο «Έλενα Βενιζέλου» σε τραχηλικά δείγματα και με τη μέθοδο PCR careGENE STD-12detection kit use με ταυτόχρονη ανίχνευση άλλων 11 ΣΜΝ σε ουρηθρικά, τραχηλικά ή πρωκτικά δείγματα. Συνολικά ελέγχθησαν 5.360 δείγματα ανδρών και …
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Newer and novel sputum versus non-sputum-based tools for the diagnosis of active tuberculosis in different patient sub-populations
… & cost efficient strategy to combine sputum GeneXpert and urine LAM (tests that are recommended by the WHO) in a hospitalized HIV-infected sub-population: This comprised a post-hoc analysis of 561 HIV-infected sputum-expectorating patients that was part of a larger parent trial. 5 different …
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The prevalence of different human papillomavirus genotypes in lesions of the uterine cervix as a method in risk assessment of cervical cancer
… PCR tests include the Cepheid Test on the GeneXpert platform, the Roche assay on the Cobas® platform and the BD OnclarityTM assay on the Viper system. The former two tests report HPV 16, 18 and a pool of ‘other' high risk genotypes on LBC samples. The latter offers extended genotyping, …