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Showing 1 to 2 of 2 for “"Gene regulatory region"”.

  1. Regulatory Regions required for β-Defensin-2 Up-regulation by Interleukin-1α in the Human Middle Ear Epithelial Cell Line

    … is unclear about signal transduction pathway and gene regulatory region of human betadefensin-2 (hBD-2). MATERIALS AND METHOD: The expression of hBD-2 by IL-1a in HMEEC (Human Middle Ear Epithelial Cell) was detected by RT-PCR. The luciferase-expressing vector containing diverse lengths of the …

    ajou Repository record for Regulatory Regions required for β-Defensin-2 Up-regulation by Interleukin-1α in the Human Middle Ear Epithelial Cell Line (opens in a new tab)

  2. Assessing the impact of non-coding mutations on breast cancer risk predisposition genes

    … patients (women diagnosed with a HBOC of unknown genetic cause), whose genetic predispositions are poorly understood. Indeed, the cause of between 50-60% of HBCs currently remains unknown, demonstrating the missing heritability of the disease. Furthermore, the role of mutations/variants in …

    qu-belfast Repository record for Assessing the impact of non-coding mutations on breast cancer risk predisposition genes (opens in a new tab)