Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Gene microarray"”.
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A comparison of gene expression in tolerated and rejected islet grafts by gene microarray analysis
… as well as their influence on intragraft gene expression, tolerated islet grafts from the described model and rejected islet grafts from untreated animals were subjected to gene expression studies. <br>Methods. Gene expression analysis in tolerated and rejected islet grafts was performed …
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Identification of Anti-Beta2 Glycoprotein I Auto-antibody Regulated Gene Targets in the Primary Antiphospholipid Syndrome Using Gene Microarray Analysis
… phenotype. In order to characterise EC gene regulation in response to anti-2GPI, early global gene expression was assessed in human umbilical vein endothelial cells (HUVEC) in response to affinity purified anti-2GPI. Sera were collected from patients with PAPS and IgG was purified …
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Thermal Ablation Alters The Tumor Microenvironment Activating A Robust Immune Response.
… compared to 16 patients treated with ablation. Gene microarray analysis and immunohistochemistry (IHC) for presence of immune cell subtypes were performed on the tissue samples. Prospectively, blood was collected from patients 13 patients who underwent renal ablation for renal cell carcinoma for …
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Elucidating the regulatory mechanisms of pterygium
… to detect cell transdifferentiation. Human angiogenesis protein array was used for investigating angiogenic activities in pterygial fibroblasts. Gene microarray was employed to provide a global profile of gene expression in unstimulated and treated (1ng/ml TGFβ2 and 10% serum) conditions. …
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Birth Defect Amelioration and Placental Cytokine Expression in Mnu-Exposed Dams Treated With Ifn-Gamma
… the dam as an immune stimulant. To determine the genes participating in these processes, gene microarray studies were conducted. Hepatocyte growth factor (HGF), interleukin 1 beta (IL1Β), and insulin-like growth factor 2 (IGF2) were elucidated as genes that were significantly expressed in GD12 …
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Development of a novel, clinically-relevant model for investigating factors that stimulate human hair growth
… types, while quantitative real-time PCR and gene microarray analysis detected their increased gene expression in intermediate follicles. Thus, smaller intermediate follicles showed major morphological and gene expression differences to terminal follicles in vivo and retained significant, …
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Model-Based Genomic/Proteomic Signal Processing in Cancer Diagnosis and Prediction
… years, high throughput measurement technologies (gene microarray, protein mass spectrum) have made it possible to simultaneously monitor the expression of thousands of genes or proteins. A topic of great interest is to study the difference of gene/protein expressions between normal and cancer …
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The role of 4-hydroxynonenal in cellular signaling mechanisms
… survival signaling by regulating expression of genes involved in these pathways, and that alteration of that level either up or down will result in induction of genes pro-apoptotic or pro-carcinogenic signaling pathways, respectively.\r\n After stable transfection of hGSTA4 in HLE B-3, cells …
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Immunoteratological Studies of Diabetic Embryopathy Using Gene Expression Analysis
… with type I diabetes. Immune defects in the pathogenesis of diabetic embryopathy have been suggested. We hypothesized that activated immune system can counteract diabetic effect and result in prevention of diabetic embryopathy. Diabetes was induced in pregnant ICR mice by streptozocin injection. …
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Statistical Methods for Genetic Pathway-Based Data Analysis
The wide application of the genomic microarray technology triggers a tremendous need in the development of the high dimensional genetic data analysis. Many statistical methods for the microarray data analysis consider one gene at a time, but they may miss subtle changes at the single gene level. …
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Molecular characterisation of odontoblast during primary, secondary and tertiary dentinogenesis. Caractérisation moléculaire de l’odontoblaste au cours des dentinogénèses primaire, secondaire et tertiaire.
… and tertiary (reactionary and reparative) dentinogenesis. Using gene microarray analysis and sq-RT-PCR, evidence is presented that the changes in secretory activity of odontoblasts reflect differential transcriptional control and that common regulatory processes may exist between dentine and bone. …
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The roles of hepatocyte growth factor family members in androgen-regulation of human hair growth. A comparison of the expression of hepatocyte growth factor family members, HGF and MSP, and their receptors, c-Met and RON, in isolated hair follicles from normal and androgenetic alopecia (balding) scalp.
… e.g. beard and causing scalp balding, androgenetic alopecia. Hair disorders cause psychological distress but are poorly controlled. Androgens probably act by altering regulatory paracrine factors produced by the mesenchyme-derived dermal papilla. This study aimed to investigate paracrine …
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Early nutrition affects intestinal development and immune response in the neonatal piglet
… IL-4, IL-10, IL-13 (Dewals et al, 2010). Gene expression of FF, CF, and SR piglets was assessed using a porcine gene microarray (Agilent). Among the 25,273 probes on the microarray, 449 were differentially expressed (FDR p<0.2). Bioinformatic analyses using MetaCore, revealed that the most …