Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 159 for “"Gene expression patterns"”.
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Gene expression patterns of encapsulated microbial cells
… matrices is vital. We analyze the gene expression patterns of stationary phase Saccharomyces cerevisiae (S. cerevisiae) cells encapsulated within three distinct nanostructured silica matrices and relate those patterns to known naturally occurring metabolic states. It was found that …
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Gene expression patterns of the female genital tract and immunomodulation by Lactobacillus species
… approach, this research aimed to investigate gene expression patterns in the FGT of HIV-infected women compared to peripheral blood. Furthermore, transcriptomics was used to investigate interactions between different vaginal Lactobacillus species and the host to elucidate its immunomodulatory …
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Using Artificial Life to Design Machine Learning Algorithms for Decoding Gene Expression Patterns from Images
Understanding the relationship between gene expression and phenotype is important in many areas of biology and medicine. Current methods for measuring gene expression such as microarrays however are invasive, require biopsy, and expensive. These factors limit experiments to low rate temporal …
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Next Generation Sequencing Reveals Gene Expression Patterns in the Zebrafish Inner Ear Following Growth Hormone Injection
… other vertebrates, the mechanism of hair cell regeneration is not possible. The molecular mechanisms that underlie this regeneration in nonmammalian vertebrates remain elusive. To understand the gene regulation during hair cell regeneration, our previous microarray study on zebrafish inner ears …
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Natural genetic variation and gene expression patterns underlying lateral shoot (tiller) development in barley (Hordeum vulgare L)
… completed to gain a better understanding of the genetic control of tiller development. One focused on characterizing natural phenotypic and genetic variation in tiller number throughout development in a large, diverse germplasm collection; and the second focused on identifying meristem-specific …
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Conclusions About Functional Relationships Between the Candida Albicans *Als Proteins Drawn From Analysis of ALS Gene Expression Patterns
"The agglutinin-like sequence (ALS) gene family of C. albicans consists of eight genes, some of which encode proteins with adhesive functions. Protein function across the entire family is unknown. The central assumption of this study was that ALS gene expression data could be used to provide …
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A Time-Course Analysis of Behavioral Plasticity and Differential Gene Expression Patterns in Response to Density in Schistocerca americana (Orthoptera: Acrididae)
… behavior did not significantly change over time. Gene expression of the following three genes suspected of having a role in behavior change were investigated based on studies of S. gregaria: protein kinase A (PKA), L-Tryptophan-5-monooxygenase (T-5), and Aromatic L-amino acid decarboxylase …
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Hypoxia-inducible factor-1 alpha (HIF-1alpha) and its role in the hypoxic preconditioning and gene expression patterns in zebrafish ( Danio rerio) embryos
… assessing Pcrit, a suite of hypoxia responsive genes were analysed by real time PCR. IGFBP-2 showed a significant decrease in expression in the HIF-1alpha deficient embryos, and EPO showed a significant increase in HIF-1alpha deficient embryos. All other genes examined showed no significant …
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Modeling transcriptomic dynamics and epigenomic conservation
Gene regulatory networks control gene expression during various biological processes, including two sets with similarity: differentiation processes of embryonic stem (ES) cells and embryo development processes. This thesis work centers on two aspects in analyses of such gene expression patterns: …
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Epigenetic Regulation Controls Intrinsic and Extrinsic Drivers of Gastrointestinal Development
… requires highly specific spatial and temporal patterns of gene expression. However, it remains unclear what forces regulate spatiotemporal gene expression patterns in the early gut. Epigenetic control of gene expression offers a possible mechanism for orchestrating the necessary gene expression …
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Transcriptional Profiling of Early Cardiac Development
Cardiogenesis is an intricate process that spans nearly the entire developmental history of the mammal. A thorough comprehension of the molecular interactions that direct cardiac development will improve our ability to understand and treat cardiovascular diseases. The earliest stages of heart …
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Illuminating the function of a master regulator of Caulobacter crescentus gene expression
… that accommodates the temporally regulated expression of functionally specialized gene products and the constitutive synthesis of stable RNAs required for ribosome biogenesis and translation. The Caulobacter crescentus cell cycle has been well-characterized and represents a powerful model …
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Statistical Analysis of Gene Expression Profile: Transcription Network Inference and Sample Classification
The copious information generated from transcriptomes gives us an opportunity to learn biological processes as integrated systems; however, due to numerous sources of variation, high dimensions of data structure, various levels of data quality, and different formats of the inputs, dissecting and …
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Evaluation of the Role of Epstein-Barr virus and Cellular Gene Expression in Paediatric and Adult Transplant Recipients
… To accomplish this, we examined EBV and cellular gene expression patterns in (i) the context of EBV lytic induction in a lymphoblastoid cell line (LCL) model system, (ii) PTLD versus non-PTLD transplant patients. In addition we examined the contributions of lytic virus replication vs. latent …
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L-Carnitine Supplementation for Periparturient Dairy Cows
… revealed that carnitine infusion altered hepatic gene expression patterns in cows fed for restricted and ad libitum feed intake. Expression of several target genes was increased by feed restriction but the effect was dampened by carnitine infusion during feed restriction, indicating that carnitine …
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The role of CD4+T cells in host protective responses against cutaneous Leishmaniasis using genome-wide transcriptomics.
… causes susceptibility to L. major. We compared gene expression patterns early during infection in CD4+ T cells in the absence or presence of IL-4Rα signaling. Non-healer BALB/c mice with a deletion of the IL-4Rα on all cells (IL-4Rα-/-) or CD4+ T cells only (iLCKcreIL-4Rαlox/-) and their …
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Fast image and data processing methods for novel neuroscience technologies
… (FISH) based pipeline for reading out gene expression from neurons. Using optimization methods, we select a compact set of genes that provide enough information to distinguish every neighboring pair of neurons in the nervous system. We show that we can process volumetric images of live …
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Gene Expression Changes in Immune Cells During Human Immunodeficiency Virus 1 (HIV-1) Infection
… system, which are reflected in the altered gene expression patterns of the immune cells. By studying these patterns through gene expression profiling it is possible to describe not only the current states the cells are in, but also to extrapolate the proximal signals that resulted in the …
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