Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Gene duplication and Loss"”.
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Phylogeny Inference in the Presence of Incomplete Lineage Sorting, Gene Duplication and Loss and Hybridization
… captures how a set of extant species split and diverged from their most recent common ancestral species. A gene tree captures the evolutionary history of an individual gene or, more generally, non-recombining genomic region. A very complex relationship exists between the phylogeny of a set …
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Methods and analysis of genome-scale gene family evolution across multiple species
The fields of genomics and evolution have continually benefited from one another in their common goal of understanding the biological world. This partnership has been accelerated by ever increasing sequencing and high-throughput technologies. Although the future of genomic and evolutionary studies …
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Novel computational methods for discordance-aware phylogenomic analysis
… set of species is a key step in many biological and medical research projects, as species trees provide a context in which problems in comparative genomics, biodiversity, phylogeography and epidemiology can be addressed. Recent advances in sequencing technologies have led to an increasing …
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Biogeochemical and phylogenetic signals of Proterozoic and Phanerozoic microbial metabolisms
Life is ubiquitous in the environment and an important mediator of Earth’s carbon cycle, but quantifying the contribution of microbial biomass and its metabolic fluxes is difficult, especially in spatially and temporally-remote environments. Microbes leave behind an often scarce, unidentifiable, or …
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Biogeochemical and phylogenetic signals of Proterozoic and Phanerozoic microbial metabolisms
Life is ubiquitous in the environment and an important mediator of Earth's carbon cycle, but quantifying the contribution of microbial biomass and its metabolic fluxes is difficult, especially in spatially and temporally-remote environments. Microbes leave behind an often scarce, unidentifiable, or …
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Computational evolutionary genomics : phylogenomic models spanning domains, genes, individuals, and species
… a wide range of evolutionary questions. In phylogenetics, methods for reconstructing gene histories from sequence data have enabled researchers to better understand how evolution shapes gene content; for example, the identification of evolutionarily-related genes has allowed for the mapping of …
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Adaptive Evolution of Surface Proteins in Microbial Pathogens: Lyme Disease Pathogens (Borreliella sp.) and Human Immunodeficiency Virus Type 1 (HIV-1)
<p>Cell and virion surface proteins are key to the survival and adaptation of microbial pathogens by enabling them to evade host immune responses and to persist in diverse environments. Pathogens respond to host immune pressures with genetic changes in surface proteins through mechanisms including …
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Supertree-like methods for genome-scale species tree estimation
… estimated from a few regions of the genome (genes), it is now widely recognized that biological processes can cause the evolutionary histories of individual genes to differ from each other and from the species tree. This heterogeneity across the genome is phylogenetic signal that can be …
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Mosquito Odorant Receptors: C-terminal Motifs, Subfamily Expansion, and Function
… likely to be disease vectors. Therefore understanding the molecular basis of this preference is important for public health. These differences may be the result of genetic variations in olfactory signaling components such as mosquito odorant receptors. This hypothesis is supported by several …