Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Gene by environment interactions"”.
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Repurposing variance genome-wide association studies (vGWAS) for identifying gene-by-environment interactions
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2023-12-04 without embargo terms
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Applications of next-generation sequencing technologies and advanced analytical methods to understand gene by environment interactions
… for high voluntary activity to a control line in environments restricting or enabling a rewarding activity. Results offered insights into genetic factors behind activity dependence and provided a model for understanding addiction and other reward-dependent behaviors.Most genes differentially …
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Molecular Genetic Basis of Opposite Gene by Environment Interactions in Reading Disability and Attention Deficit/Hyperactivity Disorder
… goal of this study is to better understand the genetic basis of Reading Disability (RD) and Attention Deficit Hyperactivity Disorder (ADHD) by examining molecular G x E interactions with parental education for each disorder. Research indicates that despite sharing genetic risk factors, RD and …
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A factor analytic-genetic approach to the relationship between morphology and behavior in mice
<p>Three hundred and seventy-seven genetically heterogeneous mice were reared on either high or low fat diets for the first forty days of life. The mice were cross fostered to permit the separation of genetic and environmental effects in a sibling analysis. A total of 26 measures were taken on …
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Potential biological embedding of adverse and enriching environments through epigenetic mediators
… ASE-associated effects in humans. In contrast, environmental enrichment (EE) can exert positive physiological and cognitive effects and can rescue the negative effects of ASEs (as observed in both humans and rodents). It appears then, that the effects of ASEs and EE potentially operate on …
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Network-based approaches towards understanding the emergence of neurodevelopmental disorders
… in psychiatry. This challenge is compounded by the complexity of neurobiological organization, spanning genes to brain systems, and by the interacting influence of environmental exposures. This thesis addresses these challenges using two complementary, network-based approaches under a …
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Bayesian Statistical Methods In Gene-Environment and Gene-Gene Interaction Studies
… diseases such as cancer result from multiple genetic changes and environmental exposures. Due to the rapid development of genotyping and sequencing technologies, we are now able to more accurately assess causal effects of many genetic and environmental factors. Genome-wide association studies …
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Nurture is Nature: The Molecular Basis of Caregiver Genotype Effects on Larval Growth and Caste Development in the Clonal Raider Ant
<p>The distinction between nature (genetics) and nurture (environment) is blurry, in part because the environment includes the genes of social partners. This is especially evident for parents and their offspring, where genes expressed in one partner profoundly influence the physiology and behavior …
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Identification of genetic loci underlying equine metabolic syndrome and laminitis risk
… disease, and identification of its underlying genetic risk factors and key gene-by-environment interactions will improve our understanding of EMS pathophysiology and allow for early detection of high-risk individuals and intervention prior to the onset of laminitis. We hypothesized that major …