Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"Gene annotation"”.
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A landscape genomic approach to investigating growth performance in South African Bonsmara cattle
… originated from four SNP array panels; GGP 80k (GeneSeek Genomic Profiler™), GGP 150k (GeneSeek Genomic Profiler™), IDB version 3 (International Beef and Dairy), and VersaSNP 50k (Weatherbys Scientific). The common SNPs across these panels were identified and quality control was conducted with …
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GOGO: An Improved Algorithm to Measure the Semantic Similarity Between Gene Ontology Terms
<p>Measuring the semantic similarity between Gene Ontology (GO) terms is an essential step in functional bioinformatics research. We implemented a software named GOGO for calculating the semantic similarity between GO terms. GOGO has the advantages of both information-content-based and hybrid …
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Develpment of soybean knowledge base for systems biology studies
… developed for SoyKB isualization analysis. The gene expression data are displayed under transcriptomics chart, scatter plot, heatmap and hierarchical clustering. The gene differential expression data are visualized under the differential expression browser, which includes volcano plot, gene …
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Expression of maize genes on a specific chromosome in the presence of a foreign genome.
… line in order to assess the prevalence of maize gene expression in an alien background. Despite the lack of gross morphological changes, we found that 26% of the maize genes that are normally expressed in maize seedlings are also expressed in OMA seedlings. All three OMA lines show very similar …
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Fine Mapping and Evolution of a QTL Region on Cattle Chromosome 3
… 3 Mbp subregion of the QTL critical region. For genes located in the QTL critical region, functions were predicted on the basis of human gene annotation. To identify orthologous genomic regions containing candidate genes, a bioinformatics tool, SyntenyTracker was developed. Within the QTL …
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Chromosomal evolution in mosquitoes - vectors of diseases
… for mapping of approximately 90% of available genetic markers to their precise positions on the chromosomes. Idiograms were integrated with 140 genetic supercontigs representing 26.5% of the genome. A linear regression analysis demonstrated good overall correlation between the positioning of …
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Improving genome assembly by identifying reliable sequencing data
… that using partial reads for assembly ii and gene prediction recovers a significant proportion of genes and propose to use this approach for rapid pathogen detection in combination with Single Cell Genomics (SCG). Thanks to SCG, it is now possible to isolate one single cell from environmental …
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CoryneRegNet : a reference database and analysis platform for corynebacterial gene regulatory networks
… factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of microorganisms deduced from literature-derived knowledge, computer predictions and global DNA microarray hybridization experiments, has opened the way for the genome-wide analysis of …
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Characterization of the expression patterns of the retrogene-parental gene pairs in the African malaria vector Anopheles coluzzii
Retrogenes are a group of functional genes produced by gene retroduplication events during evolution. It has been observed that many retrogenes have formed since the evolutionary divergence of Anopheles mosquitoes from the Aedes lineage as a result of developing heteromorphic sex chromosomes. It …
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Characterization of T-DNA integration sites within a population of insertional mutants of the diploid strawberry Fragaria vesca L.
… Rosaceae family and the high ploidy level makes genetic and molecular studies difficult. However, its commercial success because of its unique flavor and nutritious qualities has increased interest in the development of genomic resources. Fragaria vesca L. is a diploid (2n=2x=14) species with a …
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Enabling the in vitro study of long noncoding RNAs to understand their role in Plasmodium falciparum
… nucleic acids and proteins, lncRNAs can modulate gene expression at the transcriptional, post-transcriptional, translational, and post-translational levels. Determining the role of lncRNAs in the regulation of the *P. falciparum* transcriptome and proteome is imperative to further our …
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Development of a ribosome profiling protocol to study translation in the yeast Kluyveromyces marxianus
… digest unprotected mRNA, purifying the RPF and generating a cDNA library. Deep sequencing of these cDNA libraries can reveal the locations of all translating ribosomes in vivo. These data can be used to study aspects of mRNA translation including recoding (e.g. +1 frameshifting), ribosome …
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Linkage fine-mapping, GWAS and QTLs affecting morpho-agronomic traits of a common bean RIL population
… food security on the world. In this sense, genetic breeding is essential to obtain more productive cultivars, with plant architecture more adequate to the harvesting systems, with a cycle suitable to the regions of production, and grain type compatible with the requirements of the local …
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Building a robust clinical diagnosis support system for childhood cancer using data mining methods
… to single nucleotide polymorphism (SNP) and gene expression data. This research thesis focuses on three different types of data: gene-annotations, gene expression and single nucleotide polymorphisms. Genetic association studies have led to the discovery of single genetic variants associated …
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Genetic characterization of Rpp1-mediated Asian soybean rust resistance using in-depth transcriptomic and genomic analyses
… to avoid being detected by the resistant genes, and to the spectrum of resistance-associated phenotypes observed on the same soybean genotype, successful discovery of the genes that can provide qualitative or quantitative resistance would benefit breeding programs, and would advance our …
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Investigating DNA Methylation Changes in a Preclinical Murine Model of Cutaneous Squamous Cell Carcinoma
… in aging population . In addition to the general populations, there are high risk groups, such as organ transplant recipients, who are in urgent need for strategies to treat aggressive cSCC.<br/><br/>Most animal models only partly reflect the complex genetic landscape of cSCC or leave out …
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Towards an Understanding of Genetic Control of Processing Quality Traits in Blackcurrant (<i>Ribes nigrum</i> L.)
… show continuous variation, polygenic control, genes of small effects and strong influence by the growing environment; additionally, blackcurrant is a minor crop with no reference genome and existing sequence annotation is based on homology to Arabidopsis.<br/><br/>In this study high throughput …
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A Genomic Perspective on Early Embryo Development in Cattle
… groups have been investigating highly dynamic gene expression regulation during early embryo development and its relationship to embryonic phenotypes. While it has been fundamental to improve our understanding of the genetics underlying cattle embryo development and identify potential …
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Chromosome and Genome Evolution in Culicinae Mosquitoes
… among the Culicidae family of mosquitoes. Two genera, Culex and Aedes, from this subfamily have world-wide distribution and are responsible for transmitting of several deadly diseases including Zika, West Nile fevers, chikungunya, dengue, and Rift Valley fevers. Developing high-quality genome …