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Showing 1 to 1 of 1 for “"Gemitabine conjugate"”.

  1. Application of pharmaceutical technologies to improve the activity of cancer chemotherapeutic agents

    Ibrahim, Youssef Wahib NaguibThe University of Texas at Austin2015

    … an omega-3 polyunsaturated fatty acid, was conjugated to gemcitabine in the 4(N)-amine group to synthesize a new compound (DHA-dFdC). DHA-dFdC shows potent and broad spectrum cytotoxicity against all NCI/DTP60 human cancer cell lines. DHA-dFdC is also 100000-fold more cytotoxic than …

    texas Repository record