Global ETD Search

Mechanisms of Circadian Clock Control of Rhythmic Translation in Neurospora crassa

Preh, Ebimobowei OlugbengaTexas A&M University2024

… To be activated, CPC-3 forms a complex with GCN1, which helps to bring uncharged tRNAs to the tRNA binding domain on CPC-3. In Saccharomyces cerevisiae, activation of GCN2 under stress conditions requires direct interaction of GCN1 and GCN2 with ribosomes. Furthermore, CPC-3 and GCN1 levels …

tamu Repository record for Mechanisms of Circadian Clock Control of Rhythmic Translation in Neurospora crassa (opens in a new tab)

Identification of Gcn1 binding proteins and characterization of their effect on Gcn2 function : a thesis submitted in partial fulfillment of the requirements for the degree Doctor of Philosophy in Biochemistry, Massey University, Albany, New Zealand

Shanmugam, Renuka2015

massey

Control of Programmed Cell Death by GCN-1

Cho-Park, Yoon AndrewMassachusetts Institute of Technology2022

… linked with the survival and fitness of species. GCN1, a known translational regulator, has been traditionally associated with GCN-2 to activate the Integrated Stress Response in order to modulate protein synthesis in the context of stress. In the present study/thesis, we have discovered …

mit Repository record for Control of Programmed Cell Death by GCN-1 (opens in a new tab)

Evolutionary conservation and characterization of the metazoan amino acid response

Edenius, Maja LenaMassachusetts Institute of Technology and Woods Hole Oceanographic Institution2018

… pathway in model organisms, I have identified GCN1 as the branch point that links the signal generation components of the AAR pathway to downstream therapeutic effects. I then used transcriptomic and protein interaction analyses to begin to understand the scope of this pathway and identify key …

woods-hole Repository record for Evolutionary conservation and characterization of the metazoan amino acid response (opens in a new tab)

Evolutionary conservation and characterization of the metazoan amino acid response

Edenius, Maja LenaMassachusetts Institute of Technology2018

… pathway in model organisms, I have identified GCN1 as the branch point that links the signal generation components of the AAR pathway to downstream therapeutic effects. I then used transcriptomic and protein interaction analyses to begin to understand the scope of this pathway and identify key …

mit Repository record for Evolutionary conservation and characterization of the metazoan amino acid response (opens in a new tab)