Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Gatifloxacin"”.
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Characterizing population pharmacokinetic/pharmacodynamic relationships in pulmonary tuberculosis infected adults using nonlinear mixed effects modelling
… regimen or the 4-month test regimen where gatifloxacin replaced ethambutol. The pharmacokinetics of all drugs was described at first dose and steady-state using nonlinear mixed-effects modelling, and individual exposures were summarised as area under the concentration-time curve (AUC0-24) …
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Perfil de resistência aos antimicrobianos frente à pseudomonas aeruginosa isoladas de afecções oftálmicas em diversas espécies: revisão sistemática
… (levofloxacin, ciprofloxacin, nofloxacin and gatifloxacin) and to Imipenem. In the isolates were observed resistance of the 82,9% to chloramphenicol, proving not to be effective against Pseudomonas aeruginosa. This is the prove that the empirical use of this antibiotic should be better …
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Evaluating the Role of the Ocular Surface Microbiome in Dry Eye Disease Mediated Neural Dysregulation
… OSM in DED mice with topical administration of Gatifloxacin. Effects on the OSM and neural activity were monitored using conjunctival swabs and Ca2+ imaging, respectively. Our study showed that the OSM and neural activity were dysregulated in DED. In DED, we showed that the OSM was more abundant …
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Enumeration, isolation, identification and probiotic characterisation of lactic acid bacteria from Nigerian human breast milk
… All eleven LAB were sensitive to ciprofloxacin, gatifloxacin and quinupristin/dalfopristin and resistant to daptomycin. Most of the LAB were resistant to erythromycin, gentamicin tetracycline and vancomycin. Antimicrobial resistance genes for erythromycin and tetracycline were confirmed for three …
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Metabolomics and chemical library screening for antibacterial drug discovery
… metabolism e.g. capecitabine, balofloxacin, gatifloxacin. A second dimension involved screening in the presence and absence of cefoxitin to identify synergistic agents. Several drugs exhibited synergy with cefoxitin against MRSA that includes floxuridine, gemcitabine, novobiocin, rifaximin …
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Developments in the Mutant Prevention Concentration: A Novel Approach to Antimicrobial Susceptibility/Resistance Issues
… bilayer. To determine if the fluoroquinolones gatifloxacin (Gfx) and moxifloxacin (Mfx) are more active (lower MIC values) in the presence of BAK, we conducted MIC, MPC, and time-kill assays. MIC testing showed that in the presence of 3.125 to 50 µg/ml of BAK, the MIC of Gfx and Mfx decreased …