Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Gastrointestinal inflammation"”.
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Exploring the spectrum: The heterogeneity of autism and associations with gastrointestinal inflammation
… While the aetiology is unknown, higher rates of gastrointestinal (GI) issues in autism may be mediated by the gut-brain axis with dysregulated inflammation affecting the nervous system and GI homeostasis. GI inflammation is understudied and there is limited examination of intersections with the …
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The Detection of Gastrointestinal Inflammation with Microultrasound and The Feasibility of Ultrasound Capsule Endoscopy
… (CD) is a lifelong inflammatory disorder of the gastrointestinal tract. It may manifest anywhere along the gut including anatomically remote sections of the small bowel. The principal motivation behind the work described here is to meet the clinical need for improved means of diagnosis and …
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The Fecal Microbiota of Healthy and Diarrheic Calves Before, During and at Recovery From Diarrhea
The changes associated with the gastrointestinal microbiota before, during and after neonatal calf diarrhea still needs to be fully understood and described. The first chapter of this thesis reviews our current understanding of the composition of a “healthy” fecal microbiome, microbial changes …
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Synergistic inhibition of cyclooxygenases and monoacylglycerol lipase in neuropathic pain
… chronic cyclooxygenase inhibition also causes gastrointestinal inflammation and increased risk of cardiac events. Like NSAIDs, cannabinoids have analgesic and anti-inflammatory properties and reduce neuropathic pain in preclinical models. The present study investigated the analgesic effects of …
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Neurochemical drivers of visceral pain: insights into the roles of interleukin-17 and the proton-sensing G protein-coupled receptor GPR68
… target for abdominal pain in colitis. Alongside inflammation, localised tissue acidosis driven, in part, by the heightened glycolytic activity of infiltrating immune cells, further shapes nociception in the gut. For this reason, I also investigated the role of GPR68, a proton-sensing GPCR that is …
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Observational study of children with autism who have participated in hyperbaric oxgen therapy
… decreased cerebral blood flow, neurological and gastrointestinal inflammation, reduction of purkinje cells, poor immune systems, increase of heavy metals, and deficits with their myelination. When these conditions are compared to the benefits one receives in hyperbarics a correlation is noted, …
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Role of Myosin Light Chain Kinase in Binge Ethanol and Burn Injury-Induced Intestinal Barrier Dysfunction
… that ethanol increases both pulmonary and gastrointestinal inflammation as well as susceptibility to infection in burn-injured mice; however, the mechanisms of these responses are not entirely known. Moreover, after burn injury, bacteria and their products leak out of the intestinal lumen …
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Mapping the microbiota in hidradenitis suppurativa
… their metabolites, may be responsible for skin inflammation in HS. The level of pain experienced by 150 patients with HS was measured using the visual analogue scale and EQ-5D-5L questionnaires. 59 patients with HS provided faecal samples, nasal and skin swabs of affected sites for analysis. …