Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 27 for “"Gastrointestinal diseases"”.
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Dysregulation of Noncanonical NF-κB Signaling in Gastrointestinal Diseases
… an area of damage and signal tissue repair. The gastrointestinal tract is a major signaling hub for such immune responses, as intestinal epithelial cells (IECs) compose the epithelial barrier, immune cells surveillance breached barriers to regulate the gut microbiome, and intestinal stem cells …
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Atividade antiulcerogênica de Alcaloides Pirrolizidínicos obtidos a partir do Extrato Etanólico de Senecio brasiliensis: perspectivas de uma nova terapêutica preventiva e curativa das úlceras gástricas e duodenais
… utilized by folk medicine to the treatment of gastrointestinal diseases. Phytochemical analysis showed the presence of Pyrrolizidine Alkaloids (Pas) from Senecio brasiliensis. This study have a objective the obtained of PAs extract and evaluated the antiulcerogenic activity of the PAs on …
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Identifying dietary additive regulated mechanisms impacting intestinal epithelial cell responses and inflammatory processes
… factor in the development and management of gastrointestinal diseases like Inflammatory Bowel Disease (IBD). Dietary influences are now considered significant in determining an individual's susceptibility to IBD, yet much remains unknown about the long-term effects of various dietary …
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Factors influencing development and outcome of equine gastrointestinal disease
Gastrointestinal diseases are a common cause of morbidity and mortality in horses. Colic refers to clinical signs attributed to abdominal pain in horses. The pathology underlying colic is diverse, which makes accurate prediction of survival challenging. Equine Gastric Ulcer Syndrome (EGUS) is …
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The Role of the CD14 molecule in equine endotoxemia
… soluble (sCD14) in a population of horses with gastrointestinal diseases or other illnesses likely to result in endotoxemia; and identify relationships with clinical data. Animals - Part 1; 10 healthy horses. Part 2; 55 clinical cases and 23 healthy control horses. Procedure - Part 1; PBMCs were …
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Helicobacter pylori gene regulation by virulence region located sRNAs
… with Helicobacter pylori, which can lead to gastrointestinal diseases such as ulcers and gastric adenocarcinoma. Helicobacter pylori strains are genetically variable, and some contain a DNA region called the cytotoxin associated gene pathogenicity island (cagPAI) that encodes virulence …
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Some Aspects of the Biochemistry of Malabsorption from the Upper Intestinal Tract
… assess the vitamin E status of 220 patients with gastrointestinal diseases. These patients serum levels were found is be significantly lower than those of blood donor normals. The levels found correlated with the degree of ileal disease. Surgical intervention in any area of the gastrointestinal …
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Comparative pathogenesis of Yersinia enterocolitica biotypes
… for humans and it causes a wide spectrum of diseases ranging from self-limiting gastrointestinal diseases to fatal sepsis depending on the age and the immunity of the infected person. Oral ingestion of undercooked raw meat products, unpasteurised milk and contaminated water are the main …
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Development of an image based technique for assessment of colorectal epithelial integrity and function in an ovine model
… our ability to diagnose and treat numerous gastrointestinal diseases during routine endoscopy.
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Seasonal patterns of mortality in medical admissions at Groote Schuur Hospital, Cape Town: 2002-2009
… of mortality for circulatory, respiratory and gastrointestinal diseases, and cancer, are analysed. There is a brief discussion of the findings with suggestions for further research and public health interventions to reduce excess seasonal mortality in this setting. Part D is comprised of …
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E. COLI STEC MONITORING IN A ONE HEALTH APPROACH.
… STEC, particularly its association with severe gastrointestinal diseases and hemolytic uremic syndrome (HUS), this research aims to provide a comprehensive understanding of the pathogen's dynamics across human, animal, and environmental interfaces. The introduction outlines the historical …
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Influence of food intervention on enteric nervous system and enteroendocrine cells development in a small for gestational age piglet model
… age (SGA) infants predisposes these infants to gastrointestinal diseases like necrotizing enterocolitis (NEC). A SGA piglet model was used to investigate the influences of birth weight and diet on the development of the enteric nervous system (ENS) and entero-endocrine system (EES) during the …
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Neuroepithelial Signalling in the Colon
… cause of morbidity for people living with gastrointestinal diseases, however pain management remains an unmet clinical challenge. TRPV4 is a member of the vanilloid subtype of transient receptor potential ion channels and possesses pronociceptive functions in the bowel. Our recent …
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Characterizing the microbiota and profiling small non-coding RNAs in the compartments of the equine hindgut
Gastrointestinal homeostasis is a complex relationship that encompasses the host's immune response, physiology, gut structure and the microbes residing within the host. Each one of these has pathways of communication in order to keep the host in a 'healthy state' or homeostasis. While each category …
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Investigating novel therapeutic targets for treatment of visceral pain.
Abdominal pain is a common symptom of gastrointestinal disorders such as Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). However, despite the many treatments for inflammation in IBD and disordered motility in IBS patients, few therapies target abdominal pain directly, and many …
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Combining population-scale single-cell transcriptomics with germline genetics to understand the biology of inflammatory bowel diseases
Inflammatory bowel diseases (IBD) are chronic, incurable diseases of the gastrointestinal tract with a high prevalence in the United Kingdom and a growing incidence worldwide. The two most common forms of IBD are Crohn’s disease (CD) and ulcerative colitis (UC). Genome-wide association studies …
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Evaluation and Selection of a Bacillus based Direct-Fed Microbial Candidate for In situ Enzyme Production to Improve Gut Health Integrity, Bone Quality and Growth Performance in Poultry
… practice to reduce the incidence of bacterial gastrointestinal diseases. Therefore, the objectives of the present dissertation were to evaluate and select different Bacillus spp. strains as DFM candidates based on enzyme production profiles to improve nutrient absorption and intestinal …
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INNOVATIVE STRATEGIES TO IMPROVE THE SUSTAINABILITY LEVELS OF THE CATTLE PRODUCTION SYSTEMS
… resilience and resistance of the animals. Also, gastrointestinal diseases and imbalance are other causes of deprived animal welfare and reduced production efficiency during the entire fattening period. Thus, a strategy to safeguard ruminal stability and improve efficiency was evaluated. In …
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