Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Gastrointestinal cancer"”.
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Reducing the missing heritability of gastrointestinal cancer
Contains fulltext : 306672.pdf (Publisher’s version ) (Open Access)
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Molecular and Metabolic Regulation of Gastrointestinal Cancer Metastasis
<p>Most of the cancer related mortality caused by metastatic disease rather than primary tumor growth. More than 80% of gastrointestinal cancers initially metastasize to the liver first. While the prognosis of early-stage cancers is improving, a significant proportion of patients have metastatic …
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The association between oral health, related bacteria and gastrointestinal cancer risk and progression
Cancer is a worldwide public health burden, with an overall annual incidence of 18.1 million new cancer cases and 9.6 million deaths each year reported in 2018. Approximately one-third of these cases were attributable to cancers of the gastrointestinal (GI) tract. Cancer incidence and mortality …
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Physical activity and Gastrointestinal Cancer: A deeper understanding of risk and underlying mechanisms
… an important modifiable risk factor for numerous cancers, with the World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) reporting convincing evidence for a protective role of PA for cancers of the colon, breast and endometrium.<br/><br/>Despite this, evidence suggesting …
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An evaluation of the needs of patients receiving palliative care for upper gastrointestinal cancer and their main carer
Only 20% of patients at diagnosis of gastrointestinal cancer will be suitable for potentially curative surgical resection, and then only 5 -10% of these will survive to 5 years. Most individuals die within twelve months. Whilst the relief of physical symptoms is essential and contributes to …
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Management Behavior for Symptoms and Quality of Life on the Side Effects of Chemotherapy in Gastrointestinal Cancer Patients
본 연구는 위장관암환자의 항암화학요법 부작용에 대한 증상관리행위와 삶의 질을 파악하여 효과적인 중재방안 마련을 위한 기초 자료를 제공하기 위해 시도된 서술적 조사연구이다. 연구대상은 2011년 11월부터 2012년 2월까지 경기도에 소재한 A대학병원에서 항암화학요법을 받기 위해 입원한 위장관암환자 88명을 대상으로 실시하였다. 연구도구 중 부작용과 증상관리행위 측정도구는 Dodd(1984)의 항암요법일지를 번역하여 수정∙보완한 조영수(2002)의 도구를 사용하였고, 삶의 질 측정도구는 EORTC QLQ-C30 version …
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Multidrug resistance-associated protein 2 (MRP2) and oxaliplatin transport
… is currently used in the clinical treatment of gastrointestinal cancer. Efflux membrane transporters have been reported to play roles in determining the cellular accumulation and activity of platinum-based drugs, but there have been few studies of oxaliplatin. We hypothesized that the efflux …
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The application of metabolomics in human health and disease
… to ascertain whether it was possible to predict cancer associated muscle wasting from plasma metabolites in patients with upper gastrointestinal cancer (oesophageal, gastric, pancreatic) revealed that the levels of significantly altered metabolites were generally higher in patients who had lost …
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Upper gastrointestinal adenocarcinoma: associations with gastric secretory function and gender
Gastric and oesophageal cancers were responsible for more than one million deaths in 2002. Although global incidence of gastric cancer is decreasing, this malignancy is still the fourth most common cause of cancer worldwide. The incidence of oesophageal adenocarcinoma is rising rapidly, three-fold …
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The prevalence and prognostic value of abnormal body composition phenotypes in Irish oncology patients
… of unfavourable outcomes in patients with cancer. The aim of this thesis was to identify the prevalence of cancer-associated malnutrition, particularly sarcopenia and low MA in Irish oncology patients using gold standard methods and assess their impact on clinical outcomes such as tolerance …
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Stellenwert der Endosonographie mit einem curved-array Schallkopf bei Erkrankungen des Ösophagus, Magen und Pankreas
… und extramuraler Prozesse. Die EUS des oberen Gastrointestinaltraktes hat sich als technisch ausgereifte klinische Untersuchungsmethode etabliert, insbesondere im Staging von malignen Tumoren. Dies belegen vor allem Untersuchungen mit dem mechanischen Rotationsscanner. Weit weniger wurde über …
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Mechanisms by which natural polyphenols regulate the expression of cytoprotective genes
… of various degenerative diseases such as cancer, cardiovascular disease, neuro-degenerative disease and diabetes. Clinical and animal studies using fruit and vegetable extracts have shown that polyphenols abundant in plants may account for the beneficial effect of diets high in fruit and …
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Noncanonical NF-KB in Gastrointestinal Disease
… to inflammatory and neoplastic disease in the gastrointestinal (GI) system, as well as the effects of its loss on GI health. Chapter 1 opens with an overview of gastrointestinal homeostasis and inflammation, with emphasis on the particular diseases studied in this body of work. Chapter 2 …
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Optical spectroscopy for biological and biomedical applications: potentially impacting future of healthcare with research, clinical translation and education
… as an optical technique for application in cancer detection and delineation, specifications of next generation optical devices for this application, as well as tissue microstructural and biochemical features associated with carcinogenesis and organ viability for transplantation. Previous …