Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"Gastrointestinal Infections"”.
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The significance of strain diversity in the epidemiology of Camplobacter jejuni gastrointestinal infections
… C. jejuni isolates examined from sporadic human infections in the UK over a seven-month period. Associations between gene polymorphisms identified a number of prevalent genotypes and a cluster analysis of RFLP profiles identified a strong relationship between three of these prevalent genotypes. …
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Examining Tantalum-Based Photocatalysts for Photoinactivation of E. coli
… potable water sources, and can cause a host of gastrointestinal infections. It is valuable to explore alternative cost-effective, efficient ways to reclaim wastewater and sterilize potable water outside of the current methods. Solar power is a renewable energy source, which can be harnessed for …
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Isolation and Characterization of Anti-SLP Single Domain Antibodies for the Therapy of C. difficile Infection
… difficile is the leading cause of death from gastrointestinal infections in Canada. Current antiobiotic treatment is non-ideal due to the high incidence of relapse and the rise in hyper-virulent antibiotic-resistant strains. Surface layer proteins (SLPs) cover the entire bacterial surface and …
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Hyperinvasiveness in the major food-borne pathogen Campylobacter jejuni
Campylobacter jejuni is a common cause of human gastrointestinal infections. Invasion of host epithelial cells is believed to be an important virulence Mechanism of this bacterium. C. jejuni strains vary in their ability to invade the human epithelial cells and some of the strains are …
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Investigation of the prevalence of antibiotic resistant bacteria and their genes in wastewater
… agents commonly used in the treatment of infections caused by microorganisms. Due to the increased demand of antibiotics, they have become environmental pollutant to both water and soil. This have caused adverse effects to human, animals, aquatic ecosystem and in the environment in …
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Epithelial Cell Autophagy in Antibacterial Defense of the Small Intestine
… new insights into how autophagy protects against gastrointestinal infections and maintains homeostasis with the intestinal microbiota.
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An exploration of the positive and negative relationships associated with the development of asthma and atopic disorders in primary school children in Cork
… exposures, from farming environments and/or gastrointestinal infections, as shown in this thesis, strengthen the mounting evidence that microbial exposure on GALT may hold the key to the mechanisms of allergy development. In this regard, probiotics may be an area of particular interest in …
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Modulators of Innate Gut Immunity to Enteric Viral Infections: Murine Norovirus (MNV) as a Model
… as reflected by the increased burden of gastrointestinal infections at the extremes of age. In this thesis, using the Murine Norovirus (MNV) oral infection model, I aimed to characterize intestinal mucosal antiviral-responses with specific focus on the role of IELs, the impact of aging …
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Two Attempted Investigations into the Complexities of Staphylococcal Disease
… the multiple problems related to staphylococcal infections. A comparison study was made of the hospital expenses of a group of hospitalized patients whose apparently clean surgical wounds developed staphylococci, and a comparable group whose surgical wounds healed without infection.</p> <p>A …
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Rotavirus interactions with silica and natural organic matter
Rotavirus is a leading cause of gastrointestinal infections worldwide resulting in severe diarrhea and dehydration among children (Parashar et al., 2006). Rotavirus “ubiquitous” occurrence in water systems raises fundamental questions regarding interactions with surfaces that may affect its fate …
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The role of BRD4 in the innate immune response to gastrointestinal infection
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-08-01
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Computational prediction of health status from the human gut microbiome and metabolome
… kidney diseases, metabolic diseases, and gastrointestinal infections like Clostridioides difficile infection (CDI). Often, microbiome-linked illnesses arise after the microbiome is disrupted, such as by antibiotic treatment. However, because the microbiome is so diverse and …
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An investigation into the effects of shape and structure on the antibacterial efficacy of metal nanoparticles
… or vomiting. Enterococci frequently causes gastrointestinal infections, urinary tract infections, hepatobiliary sepsis, endocarditis as well as hospital-acquired infections, e.g. nosocomial bacteraemia and surgical wound infection. As regards E. coli, NHS trusts in England reported 38,132 …
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Small Molecule and Macromolecular Donors of Reactive Sulfur Species: Insights into Reactivity and Therapeutic Potential
… bacteria, opportunistic pathogens implicated in gastrointestinal infections. Lastly, two appendices are provided in this dissertation that briefly describe the synthesis of a pyrene-based H2S sensor and efforts toward a readily accessible peptide-based thioacids as H2S donors.
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REGULATION AND EXPRESSION OF AMYLOID CURLI IN SALMONELLA INFECTION
… mice during infection. Furthermore, bacterial infections are important environmental triggers of autoimmunity and can contribute to autoimmune disease onset and severity. Here, we investigated the synthesis of curli in the gastrointestinal tract during Salmonella infection and how host-derived …
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Impact of early nutrition on the development of lung immunity in the piglet
… infection early in life, especially respiratory infections (Murphy et al. 2008). Respiratory infections are a major cause of morbidity and mortality in infants and children world-wide. The immune system exists to protect the host against infection and to help the neonate respond appropriately to …
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Impatto di rifaximina sul microbiota intestinale: selezione di bifidobatteri antibiotico resistenti
… compound, rifamycin, in order to achieve low gastrointestinal absorption while retaining good antibacterial activity. Both experimental and clinical pharmacology clearly show that this compound is a non systemic antibiotic with a broad spectrum of antibacterial action, covering Gram-positive …