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Showing 1 to 1 of 1 for “"Gamma-secretase-mediated proteolysis"”.

  1. Investigation of p75 neurotrophin receptor and the role of its post-translational modifications in tumour cell motility and invasiveness

    … Recently,p75NTR was also shown to undergo γ-secretase-mediated regulated intramembrane proteolysis, and the receptor ICD was found to migrate to the nucleus where it regulates gene transcription. Moreover, γ-secretase-mediated proteolysis was shown to be involved in glioblastoma cell …

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