Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Galantamine"”.
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Long Term Outcome and Prediction Models of Cognition, Activities of Daily Living and Nursing Home Placement in Alzheimer’s Disease with Cholinesterase Inhibitor Treatment
… patients treated with donepezil, rivastigmine or galantamine III. 790 patients treated with donepezil, rivastigmine or galantamine IV. 880 patients treated with donepezil, rivastigmine or galantamine Results I. Regression models predicted 3-year cognitive outcome in ChEI-treated patients with high …
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Influence of a Nicotinic Treatment on Auditory Sensory Processing in Schizophrenia
… with selective α7 nAChR agonist properties and galantamine, a nAChR positive allosteric modulator (PAM), which was posited to augment α7 nAChR signalling. Auditory sensory processing was examined with ERP paradigms assessing two functions commonly impaired in SCZ; (a) the ability to inhibit …
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Long-term treatment response, predictors and biochemical markers in Alzheimer’s disease.
… (ChEIs) (tacrine, donepezil, rivastigmine, galantamine) were introduced as treatments for AD. Multiple short-term randomised clinical trials of ChEI treatment show beneficial effects on cognition, global functioning and activities of daily living in AD. Whether the effects of long-term ChEI …
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The effects of anticholinesterases and β-amyloid pathology on neurotrophin signaling in the mouse brain
… in the mouse brain. We show that donepezil and galantamine, two clinically used ChEis, rapidly phosphorylated Trk receptors in the mouse hippocampus. Subsequent pharmacological studies suggest that cholinergic activation of Trk receptors required simultaneous stimulation of nicotinic and …
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Changes in cerebral glucose metabolism in patients with Parkinson’s disease with dementia after cholinesterase inhibitor therapy
… Patients were treated with either donepezil or galantamine. End point was when patients were treated for at least 3 months and when the patient or family members reported improved cognition. 18F-FDG PET scan was done before initiation of treatment and after completion drug trial. SPM images were …
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CUMULATIVE ANTICHOLINERGIC BURDEN AND ASSOCIATED OUTCOMES AMONG OLDER ADULTS WITH ALZHEIMER’S DISEASE
… any of the ChEIs (donepezil, rivastigmine, or galantamine). The cumulative anticholinergic burden was calculated based on the Anticholinergic Cognitive Burden scale and patient-specific dosing using the defined daily dose over the defined period after ChEIs initiation. For objective 1, the …
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Natural Products Chemistry of Leads Acting on MRSA, HCV, Malaria, and Depression Disorders
… (foxglove) for treatment of heart disease, galantamine from Galanthus caucasicus (snowdrops) for treatment of Alzheimer's disease, and paclitaxel from the bark of the Pacific yew tree to treat cancer. </p> <p>During the course of these studies, we researched the potential of natural products …