Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 20 for “"Galanin"”.
-
Expression and Function of Galanin in Colonic Sensory Neurones
… potential to identify new therapeutic avenues. Galanin is a neuropeptide that has various functions within the central and peripheral nervous systems, e.g. regulation of feeding and modulation of nociceptive pathways respectively. Galanin has been previously demonstrated to modulate the …
-
Galanin-like peptide: a molecular link between energy homeostasis and reproduction
Galanin-like peptide (GALP) shares partial sequence identity with galanin and exhibits agonistic activity at galanin receptors (GALR1 and GALR2) in vitro. GALP neurons almost exclusively reside within the arcuate nucleus, a region of the hypothalamus that plays a pivotal role in the control of body …
-
Neuropeptides and neurotrophic factors in epilepsy: seizure suppressant actions of VEGF, NPY and galanin
… growth factor (VEGF), neuropeptide Y (NPY), and galanin. To study these molecules, we have used different animal models of epilepsy and investigated the effect on epileptic seizures by enhancing the expression of these endogenously occurring proteins and/or their receptors in the brain of …
-
Role of galanin in synaptic transmission and plasticity in the CA1 area of the rodent hippocampus
Galanin is believed to be co-released with acetylcholine by neurones projecting from the medial septum and nucleus ofMeynert to the hippocampus in rodents. Galanin inhibits acetylcholine and glutamate release, thereby depressing excess neuronal excitability in the brain. Although this effect …
-
Antwortverhalten Galanin-immunoreaktiver isolierter Spinalganglienzellen der Ratte auf Hitze- und Capsaicinstimulation in Abhängigkeit von neurotrophen Faktoren
… der Literatur ist bekannt, dass das Neuropeptid Galanin in Verhaltensexperimenten an Galanin-KO Mäusen eine wichtige Rolle bei der Entwicklung einer thermischen Hyperalgesie spielt. Welche Membrankanäle noxische thermische Reize in galaninergen Nozizeptoren transduzieren, wurde nicht …
-
Über den Zusammenhang von Galaninexpression und Capsaicinempfindlichkeit in Spinalganglionneuronen von Ratten mit experimentellen Nervenverletzungen
… der Capsaicinempfindlichkeit und der Galaninexpression in einzelnen Spinalganglionneuronen unter verschiedenen Bedingungen untersucht. Diese Eigenschaften wurden gewählt, weil beide nach experimentellen Nervenverletzungen starken Veränderungen unterliegen und weil beide über „nerve …
-
Characterization Of Neuronal Groups Regulating Sexual And Agonistic Behavior In Male Chicken (Gallus Gallus)
… behavior, respectively. Immunostaining for AVT, galanin, serotonin and gonadotropin-releasing hormone (GnRH) were compared between aggressive and non-aggressive males to test their behavior functions. Galanin fiber density in the SL was higher in aggressive males than non-aggressive males and …
-
Modulation of mechanosensitive gastro-oesophageal vagal afferents by novel targets.
… chosen for study in this thesis. These are: 1) Galanin receptors, which may be excitatory or inhibitory GPCRs depending on their subtype 2) Excitatory ionotropic glutamate receptors, and their relative contribution compared with excitatory metabotropic glutamate receptors. 3) Ghrelin receptors, …
-
Interactions of islet hormones with acetylcholine and cholecystokinin-octapeptide in the isolated pancreas of normal and diabetic rats
… vasoactive intestinal polypeptide (VIP) and galanin, the islet hormones insulin, glucagon and somatostatin, the neurotransmitter acetyicholine (ACh), the gut hormone cholecystokinin octapeptide (CCK-8), sodium nitroprusside (SNIP), 8-Bromo guanosine 3'5' cyclic monophosphate (8-Br cOMP) and …
-
Activity Based Profiling: New Insights into Metabolic Homeostasis
… neurons during scheduled feeding and the role of galanin neurons in maintaining body weight.</p>
-
Effects of exogenous and endogenous factors on appetite regulation in broiler chicks and Japanese quail
… there was a decrease in mRNA abundance of galanin, ghrelin, melanocortin receptor 3, and pro-opiomelanocortin (POMC), however within the ARC there was a decrease in POMC and an increase in c-Fos mRNA after FA treatment. OXM, a proglucagon-derived peptide produced in the gastrointestinal …
-
Relationality over Coloniality: An Inquiry into Decolonizing Settler-isms with Indigenous Futurisms
… world. Multidisciplinary artists, Nicholas Galanin, Steven Paul Judd, and Andy Everson reimagine Star Wars with space NDNs (N-D-N-s) highlighting the connective tissue of Indigenous living presence in past-present-future timelines. In conclusion, I suggest that if there is to be any hope of …
-
Behavioural and Metabolic Characterization of NPR-9 and AIB Signaling Dynamics in Caenorhabditis Elegans
… behaviours. Previous work has highlighted that galanin-like G-protein coupled neuropeptide receptor NPR-9 and stimulatory glutamate gated cation channel receptor GLR-1 function in anterior interneuron AIB. npr-9 loss-of-function and over-expression mutants display abnormal spontaneous locomotion …
-
The Functional Characterization of the Quorum Sensing E. Coli Regulators B and C in EHEC
… or intestinal hormones, including gastrin, galanin, and secretin. Additionally, autophosphorylation can be antagonized upon the addition of phentolamine, an a-adrenergic receptor antagonist. Given that enterocytes harbor a-adrenergic receptors, it would be consistent for a microbial …
-
Microdialysis to study the Gastrin-ECL cell Axis in the conscious rat
… G-cell gastrin mobilization while somatostatin, galanin and bradykinin were found to inhibit omeprazole-induced gastrin mobilization.
-
Sampling strategies for characterization of neuropeptides using mass spectrometry and functional implications into cell-cell signaling
… angiotensin I, somatostatin-14, neurokinin B, galanin, and vasoactive-intestinal peptide (VIP) were detected in the SCN only. Lists of peptides were generated from both brain regions for comparison of the peptidome of SON and SCN nuclei. Moving from analysis of magnocellular neurons in tissue …
-
Characterization and spatial mapping of isomerized residues in neuropeptides
Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2027-08-01