Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"GZMK"”.
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Expression of perforin and granzyme variants in adult rat testes after ethylene dimethane sulfonate (EDS)-induced testosterone depletion
… cell apoptosis, the mRNA levels for grankyme K (GzmK) and perforin (Prf) were also significantly higher (2- and 2.5-fold, respectively) in EDS-treated rats compared to controls. After testosterone replacement, the levels of GzmK and Prf mRNAs were restored. The mRNA levels for Cd4 and Cd8 were …
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INTRA-TUMORAL INFILTRATION OF GZMKHIGH CD8+ T EFFECTOR MEMORY CELLS IS ASSOCIATED WITH POOR CLINICAL OUTCOME IN NON-METASTATIC COLORECTAL CANCER.
… T effector memory cells skewing them to produce GZMK, associated with tumor progression in CRC patients. Our fundings identify a unique immune signature, which might inform therapeutic decision making, possibly leading to new immunotherapeutic targets.
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ROLE OF IL-10 PRODUCING EOMES+ TR1-LIKE CELLS IN MELANOMA
… a Tr1-like population expressing granzyme K (GzmK). Performing a Differential Gene Expression (DEG) analysis on Tr1 cells, we observed no significant differences between OVA− and OVA+ cells. However, we identified differentially expressed genes between untreated and anti-PD-L1-treated mice, …