Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"GTP cyclohydrolase I"”.
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Metabolic engineering of the pterin branch of folate synthesis by over-expression of a GTP cyclohydrolase I in peanut
… acid. To increase folate levels in peanut seed, GTP cyclohydrolase I from Arabidopsis thaliana (AtGCHI) was introduced into peanut by biolistic transformation. Plant transformation vectors were constructed using publicly available or licensable vector components to avoid intellectual property …
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A clinical and molecular genetic study into familial and sporadic Parkinson’s Disease
… I report a novel missense mutation in the GTP cyclohydrolase I gene (GCH1) in a kindred with phenotypes ranging from PD to Dopa-responsive dystonia. The association of this novel GCH1 mutation with late onset parkinsonism suggests a potential role for GCH1 in PD.
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Identification and Characterization of the Enzymes Involved in Biosynthesis of FAD and Tetrahydromethanopterin in Methanocaldococcus jannaschii
… coenzyme. This intermediate is produced from GTP by MptA (MJ0775 gene product), a new class of GTP cyclohydrolase I. An Fe(II)-dependent cyclic phosphodiesterase (MptB, MJ0837 gene product) hydrolyzes the cyclic phosphate of H₂N-cP to a mixture of 7,8-dihydro-D-neopterin 2'-monophosphate and …
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Target regulation and prioritization by the small RNA SgrS in Escherichia coli
… arginine decarboxylase gene activator, GTP cyclohydrolase I and a repressor of purine biosynthesis, respectively. SgrS represses translation of each of the four target mRNAs via distinct mechanisms. SgrS binding sites overlapping the Shine-Dalgarno sequences of adiY and folE mRNAs …