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Showing 1 to 2 of 2 for “"GTP Phosphohydrolases"”.

  1. Mechanistic Analysis of Microtubule Dynamics and Regulation

    … of the microtubule, depends on the functional GTPase behavior of the microtubule polymerizing subunits, αβ-tubulin. Recent studies have noted the presence of multiple conformational states of αβ-tubulin in the microtubule lattice, in addition to major conformational changes that occur in …

    utswmed Repository record for Mechanistic Analysis of Microtubule Dynamics and Regulation (opens in a new tab)

  2. FRET-Based Conformational Sensor for the m1 Muscarinic Cholinergic Receptor

    … are the outcome of a regulated cycle of GTP binding and hydrolysis. Binding of GTP, which activates G proteins, is promoted by an agonist-activated receptor; and hydrolysis of bound GTP, which deactivates G proteins, is accelerated by a GTPase-activating protein (GAP). These two processes …

    utswmed Repository record for FRET-Based Conformational Sensor for the m1 Muscarinic Cholinergic Receptor (opens in a new tab)