Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"GSTA1"”.
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Structural Dynamics and Reaction Reversibility of Specific vs. Promiscuous Detoxification Enzymes
… 3A4 (CYP3A4) and glutathione transferase A1-1 (GSTA1-1) with that of structurally related, substrate-specific counterparts CYP19A1 and GSTA4-4. Two aspects of enzyme behavior are considered: (I) structural dynamics in the absence and presence of ligands, and (II) reversibility of …
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Exposure, health effects, immunological markers and biomarkers of susceptibility among Swedish rubber workers
… found for GSTT1. The effects of polymorphism in GSTA1-52 (G/A+A/A) on symptoms in exposed workers showed a consistent pattern of a protective effect. The results indicate that workers in the contemporary rubber industry develop symptoms and thus, the work environment should be further improved. …
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Polymorphismen der Glutathion-S-Transferase A1 in Zusammenhang mit malignen hämatologischen Erkrankungen
Seit längerem sind Fremdstoff-metabolisierende Enzyme (FME) Untersuchungsgegenstand verschiedener Forschungsgruppen. Es wurde eine Reihe von Polymorphismen der FME beschrieben, die mit einer erhöhten Suszeptibilität bezüglich der Entstehung verschiedener Malignome assoziiert werden konnten. …