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Showing 1 to 2 of 2 for “"GSK-3β inhibitor"”.

  1. Regulation of Foxc2 Expression and Function During Epithelial-Mesenchymal Transition By Gsk-

    … revealed two potential phosphorylation sites for GSK-. Furthermore, inhibition of GSK-significantly reduces FOXC2 protein. In addition, exposure of HMLE Twist cells expressing endogenous FOXC2 to the GSK- inhibitor, TWS119, results in accumulation of FOXC2 protein in the cytoplasm with …

    uthsc Repository record for Regulation of Foxc2 Expression and Function During Epithelial-Mesenchymal Transition By Gsk-3Β (opens in a new tab)

  2. The impact of glucotoxicity on pancreatic β-cell function

    … to chronic hyperglycemia. cAMP analogue or PDE inhibitors counteract these abnormalities and restore β-cell function at least in part, by activating cyclic AMP/PKA system. Using two different diabetic animal models i.e. mild hyperlipidemic ZDF (fa/fa) and hyperglycemic GK rat, we found that …

    lund Repository record for The impact of glucotoxicity on pancreatic β-cell function (opens in a new tab)