Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"GRP94"”.
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Mechanisms of Molecular Chaperone Surface Binding and Endocytosis: Insights into the Molecular Basis for GRP94 Immune Function
<p>Extracellular GRP94 can elicit both innate and adaptive immune responses by interacting with endocytic and signaling receptors on professional antigen presenting cells (pAPCs). CD91 was the first receptor proposed to facilitate GRP94-mediated immune responses. Using a GRP94 affinity matrix, a …
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Relationships Between Expression of Heat Shock Protein Genes and Photosynthetic Behavior During Drought Stress in Plants
… analyses showed that a pine homolog to GRP94 (ER-resident HSP90) was up-regulated after rehydration coincident with acclimation. This GRP94 is closely related to GRP94 from the desiccation tolerant plant X. viscosa, supporting the importance of this gene during acclimation to water …
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Regulation of autophagy, endoplasmic reticulum and unfolded protein response by glucocorticoids in physiology and disease
… in increase of ER chaperone proteins GRP78 and GRP94 in CEM-C7-14 cells. This is potentially related to increased cell death and may play a role in ER stress mediated cell apoptosis. Protein degradation inhibition by BTZ sensitised the ALL cells to the treatments and combination conditions had …
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Isolation and characterisation of an Hsp90 homologue from the resurrection plant Xerophyta viscosa
… sequence identity with the ER-Iocated Hsp90 or Grp94 family of proteins (hereafter referred to as XVGrp94) and forms the basis of this work. The XVGrp94 eDNA was found to be truncated at the 5· terminus and a full length eDNA was isolated using SMART-RACE™ (§witching Mechanism gt 5' end of RNA …
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Anbindung und Aufnahme von Hitzeschockprotein-Antigenkomplexen durch Antigenpräsentierende Zellen
… für die Hitzeschockproteine Hsp90, GRP94, Hsp70 und Calreticulin auf Raw264.7 Zellen beschrieben. Unter den in der vorliegenden Arbeit verwendeten Bedingungen exprimierten Raw264.7 Zellen sowohl vor als auch nach LPS Stimulation funktionelles CD91, wobei die Fähigkeit Hsp70 zu binden …
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PHYTOCHEMICAL AND SYNTHETIC INVESTIGATIONAL COMPOUNDS AS MODULATORS OF CYTOMETABOLIC AND CYTOSKELETAL DYNAMICS FOR PRE-CLINICAL TARGETING OF PROSTATE CANCER
… key targets in ER stress signaling (CHOP, ATF4, GRP94, GRP58, GADD 34, and PGC1α), increased glucose uptake and glycolysis due to severe nutrient and energy reduction in cells, and interfered with the cellular recovery process, autophagy, thus leading to reduced cell proliferation, activation of …
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Effects of prepartum dietary energy and lipid supplementation on hepatic transcriptome profiles in dairy cows during the transition period
… and oxidative stress indicator genes XBP1, PERK, GRP94 and HSP40 was lower in OVE than CON but TRB3, HSPA1A, HSPA1B and CREB3L3 had greater (Diet × Time; P < 0.05) expression in OVE. Expression postpartum of the inflammatory genes NFKB1, RELA, CHUK, MYD88, TNF, SAA3, and PTX3 increased (Diet × …