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Showing 1 to 1 of 1 for “"GRN-300"”.
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SIK2 Inhibitor GRN-300 Enhances Sensitivity to Paclitaxel Treatment in Triple-Negative Breast Cancer
… and Greenfire Biologics, we developed ARN-3261/GRN-300, a novel orally administered SIK2 inhibitor and evaluated its ability to sensitize TNBC cells to paclitaxel in vitro and in vivo. GRN-300 demonstrated strong synergy with paclitaxel in 8 of 9 TNBC cell lines tested, as indicated by …